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The Molecular Biologic Study about the Role of Deubiquitination Gene in Bladder Tumor Progression

Kim HY, Lee YG, Lee SE

  • KMID: 2292517
  • Korean J Urol.
  • 2002 Dec;43(12):1019-1023.
PURPOSE: Ubiqutin-proteasome-mediated proteolysis is an important pathway of nonlysosomal protein degradation, which controls the timed destruction of cellular regulatory proteins of the p21, p27, p53 gene (p53), Retinoblastoma gene (Rb),...
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Functional Studies of Acyl-CoA Synthetase 4 in the Rat Liver

Jeong YH, Moon SJ, Kang MJ

  • KMID: 1618343
  • Korean J Nutr.
  • 2003 May;36(4):376-381.
Acyl-CoA synthetase 4 (ACS4) is an arachidonate-preferring enzyme abundant in steroidogenic tissues. We examined ACS4 in rat liver, which contains a variety of pathways that use acyl-CoAs, in order to...
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Analysis of PDL Fibroblast Change During Mechanical Stimuli in the Rats

Kim TG, Kim CS, Cho KS, Chai JK, Kim CK, Choi SH

Periodontal disease is characterized by inflammation and subsequent loss and/or damage to tooth-supporting tissues such as bone, cementum, and periodontal ligament.Periodontal ligament and cementum are the key tissues in the...
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Changes in Expression of BCL-2, BAX and ICE mRNA After Middle Cerebral Artery Occlusion in Rat

Cho YH, Kim JK, Kim KK, Cho KH, Kim SJ

  • KMID: 1905138
  • J Korean Neurol Assoc.
  • 1999 Jul;17(4):568-573.
BACKGROUND: In order to delineate the involvement of apoptotic death in post-ischemic cerebral infarction, the temporal expressions of some apoptosis-regulating genes (BCL-2, BAX and ICE) were studied in the parietofrontal...
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Identification of Differentially Expressed Radiation-induced Genes in Cervix Carcinoma Cells Using Suppression Subtractive Hybridization

Kim JS, Lee YS, Lee JH, Lee WH, Seo EY, Cho MJ

  • KMID: 2323841
  • J Korean Soc Ther Radiol Oncol.
  • 2005 Mar;23(1):43-50.
PURPOSE: A number of genes and their products are induced early or late following exposure of cells to ionizing radiation. These radiation-induced genes have various effects on irradiated cells and...
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Expression of extracellular martix genes in scleroderma fibroblast cultures

Lee KS, Kim SJ, Suh MH, Song JY

  • KMID: 2303618
  • Korean J Dermatol.
  • 1991 Jun;29(3):322-330.
Scleroderma is a connective tissue disease characterized by excessive accumulation of collagen in skin and visceral organs due to increased collagen production by scleroderma fibroblasts. The basic etiology of this...
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Plasmin System in Placenta from Women with Normal and Preeclamptic Pregnancy

Roh CR, Lee JH, Yoon BK

  • KMID: 2261361
  • Korean J Obstet Gynecol.
  • 1999 Mar;42(3):539-543.
OBJECTIVES: the aim of this study was to evaluate plasmin system in placenta fiom women with normal and preeclamptic pregnancy. METHODS: The levels of urokinase-type plasminogen activator(uPA), tissue-type plasrninogen activator(tPA),...
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Expression of BRCA1 Transcripts and Protein in Sporadic Ovarian Cancer

Park CS, Kim JK

  • KMID: 2261114
  • Korean J Obstet Gynecol.
  • 1998 Aug;41(8):2131-2145.
Recently the breast cancer susceptibility (BRCA1) gene on chromosome 17q has been isolated and identified as a tumor supressor gene that is mutated in many cases of inherited breast and...
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Changes of mRNA Expression of Dopamine Receptor in the Visually Deprivated Rat Striatum

Seo SW, Yoo JM

  • KMID: 2206694
  • J Korean Ophthalmol Soc.
  • 2003 Sep;44(9):2153-2160.
PURPOSE: To investigate the changes of the dopaminergic system in rat striatum after visual deprivation during a critical period of postnatal development. METHODS: The changes of dopamine D1 and D2...
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Cyclosporin A Inhibits Albumin Synthesis in Huh7 Cells

Jeon YJ, Kim YS

BACKGROUND/AIMS: Hypoalbuminemia occurs frequently in renal transplant recipients immediately after renal transplantation. We studied the regulation of hepatic albumin synthesis by cyclosporin A (CsA) in Huh7 cells. METHODS: Huh7 cells were...
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The Production of Phospholipase A2 in Different Types of Cultured Human Intervertebral Disc Cells

Kim DJ, Wang JM

  • KMID: 2322800
  • J Korean Soc Spine Surg.
  • 2000 Mar;7(1):1-8.
STUDY DESIGN: Evaluation of phospholipase A2 production according to cell type of human intervertebral disc. SUMMARY OF LITERATURE REVIEW: It was reported that the phospholipase A2 activity in human lumbar disc...
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Expression and Localization of the PlGF mRNA in Preeclamptic Placentas

Lee SA, Noh GS, Choi WJ, Lee JH, Paik WY

  • KMID: 2129001
  • Korean J Obstet Gynecol.
  • 2002 Oct;45(10):1778-1784.
OBJECTIVE: To identify and localize the Placenta Growth Factor (PlGF) mRNA in term placentas and to determine whether there are any differences in the expression of PlGF mRNA in the...
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Fine Structure and Albumin Gene Expression in Intrasplenically Transplanted Hepatocytes

Kwon SO, Lee DK, Kim JM, Park ER, Shim KY, Jung PH, Cho MY, Hur MU

  • KMID: 2251596
  • Korean J Med.
  • 1997 Oct;53(4):534-540.
BACKGROUND: The morphological characteristics of hepatocytes transplanted into the spleen have been studied. However few attempts has been made to determine the expression of genes in intrasplenically transplanted hepatocytes. The...
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Detection of the Steroidogenic Acute Regulatory(StAR) Protein in Human Testicular Tissue

Ryu SB, Jeong DW, Oh BR, Kim SJ, Soh JM

  • KMID: 2290160
  • Korean J Urol.
  • 1998 Aug;39(8):793-797.
PURPOSE: A crucial event in the acute regulation of steroidogenesis by tropic hormone is the delivery of cholesterol from cytosol into the mitochondrial inner membrane where it is converted to...
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Changes of beta-Adrenergic Receptor mRNA in the Visual Cortex and Superior Colliculus of Monocular Deprivated Rat

Shim JH, Seo SW, Yoo JM

  • KMID: 2337152
  • J Korean Ophthalmol Soc.
  • 2004 Sep;45(9):1554-1559.
PURPOSE: To investigate the change of the Beta adrenergic system in the rat visual cortex and superior colliculus after visual deprivation during a critical period of postnatal development. METHODS: The...
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Apoptosis and Expression of bcl-2, bax in the Cyclic Human Endometrium

Suh CS, Moon SY

  • KMID: 2075934
  • Korean J Obstet Gynecol.
  • 1999 Nov;42(11):2446-2457.
OBJECTIVE: To understand the regulatory mechanism of apoptosis by pro- and anti-apoptotic genes in the cyclic human endometrium. METHODS: Each case of endometrial status was classified by Noyes criteria, and...
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Invasion Suppressor Role of E-Cadherin in Epithelial Cancer Cell Lines

Roh JY, Lee CJ

BACKGROUND: The generation of the invasiveness in transfromed cells represents an essential step of tumor progression. The primary cause of the scattering of the cells in invasive carcinoma is a...
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Expression of Placental Gelatinases in Normal and Preeclamptic Pregnancy

Roh JR, Oh WJ, CHoi JJ, Moon JS, Hwang JD, Yang SH

  • KMID: 2261394
  • Korean J Obstet Gynecol.
  • 1999 Jun;42(6):1196-1200.
OBJECTIVES: The aim of this study was to compare activities of gelatinases and their regulators in normal and preeclamptic placenta tissue. METHODS: The activities of gelatinase A and B were...
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Expression of Basement Membrane Gene in Cultured Skin Fibroblasts from Patients with Diabetes Mellitus

Kim BC, Lee KS

BACKGROUND: Bullous eruption of diabetes(BD) is a rare cutaneous sign of diabetes mellitus(DM). The mechanism for the development of these lesions is unknown, although speculation has ranged from trauma to...
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Dedifferentiation of Human Chondrocyte in Monolayer Culture and its Reversibility in Pellet Culture

Min BH, Woo JI, Park SR, Park HJ, Kang SY

  • KMID: 2141818
  • J Korean Orthop Res Soc.
  • 1998 Apr;1(1):23-31.
Articular cartilage is a unique tissue devoid of blood and nerve tissue and so its regeneration is very limited. Recently a clinical trial on transplantation using autologous chondrocyte with periosteal...
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