- Hypermethylation of Tumor-related Genes in Genitourinary Cancer Cell Lines
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Chung WB, Hong SH, Kim JA, Sohn YK, Kim BW, Kim JW
- KMID: 648358
- J Korean Med Sci.
- 2001 Dec;16(6):756-761.
- doi: 10.3346/jkms.2001.16.6.756
Hypermethylation of CpG island is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed 13 genitourinary cancer cell lines for aberrant DNA methylation of... -
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- A PCR-RFLP method for the detection of activated H-ras oncogene with a point mutation at codon 12 and 61
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Hong SJ, Lee T, Park YS, Lee KO, Chung BH, Lee SH
- KMID: 1728886
- Yonsei Med J.
- 1996 Dec;37(6):371-379.
- doi: 10.3349/ymj.1996.37.6.371
To investigate the incidence of the H-ras gene activation in bladder tumor and the feasibility of using urinary washout samples for screening, a series of 33 human bladder tumors and... -
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- P70S6K and Elf4E Dual Inhibition Is Essential to Control Bladder Tumor Growth and Progression in Orthotopic Mouse Non-muscle Invasive Bladder Tumor Model
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Chi BH, Kim SJ, Seo HK, Seo HH, Lee SJ, Kwon JK, Lee TJ, Chang IH
- KMID: 2133310
- J Korean Med Sci.
- 2015 Mar;30(3):308-316.
- doi: 10.3346/jkms.2015.30.3.308
We investigated how the dual inhibition of the molecular mechanism of the mammalian target of the rapamycin (mTOR) downstreams, P70S6 kinase (P70S6K) and eukaryotic initiation factor 4E (eIF4E), can lead... -
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- Metabolic Pathway Signatures Associated with Urinary Metabolite Biomarkers Differentiate Bladder Cancer Patients from Healthy Controls
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Kim WT, Yun SJ, Yan C, Jeong P, Kim YH, Lee IS, Kang HW, Park S, Moon SK, Choi YH, Choi YD, Kim IY, Kim J, Kim WJ
- KMID: 2374116
- Yonsei Med J.
- 2016 Jul;57(4):865-871.
- doi: 10.3349/ymj.2016.57.4.865
PURPOSE: Our previous high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry study identified bladder cancer (BCA)-specific urine metabolites, including carnitine, acylcarnitines, and melatonin. The objective of the current study was to determine... -
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