- Effects of Exposure of Propidium Iodide and Bisbenzimide on Differential Staining of Mouse Blastocysts
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Park KS, Park SB, Lee TH, Chun SS, Song HB
- KMID: 1566329
- Korean J Fertil Steril.
- 2002 Dec;29(4):317-322.
OBJECTIVE: These experiments were conducted to investigate the optimal expose length of propidium iodide (PI) and bisbenzimide on differential staining of mouse blastocysts. MATERIALS AND METHODS: A total 964 blastocysts (early~hatched)... -
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- Induction of Apoptosis and Inhibition of Cellular Proliferation in Aspirin-treated SNU-668 Human Gastric Adenocarcinoma Cell Lines
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Kim JH, Kim RH, Yoo K
- KMID: 2007129
- J Korean Cancer Assoc.
- 2001 Feb;33(1):71-76.
PURPOSE: The aims of this study was to examine the anti-proliferative effect and apoptosis induction by aspirin using SNU-668 human gastric adenocarcinoma cell lines. MATERIALS AND METHODS: After treating SNU-668 cell... -
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- Study on the Mitochondrial Dysfunction by p53 Regulation in Ceramide-induced Neuronal Cell Death
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Lee DY, Lee HJ, Noh YH, Yun JY, Han IS, Chung YH, Kim KY, Kim SS, Lee WB
- KMID: 1512990
- Korean J Phys Anthropol.
- 2006 Mar;19(1):49-59.
Ceramide induces cell death in a dose- and time-dependent manner in neuroblastoma SK-N-SH cells. To investigate the mechanism of SK-N-SH cell death by C2-ceramide, morphological features and Hoechst 33258 staining... -
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- ATP and Adenosine Induce Growth Inhibition and Apoptosis in Human Trophoblast-like (TL) Cell Line
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Park IY, Lee JH, Lee KH, Yang DE, Moon HB, Kim SJ, Shin JC
- KMID: 2272036
- Korean J Obstet Gynecol.
- 2003 May;46(5):952-956.
BACKGROUND: Although nucleotides -like Adenosine Triphosphate (ATP) and its derivatives Adenosine, were known to induce growth inhibition and apoptosis in diverse cell lines, little is known about their effects on... -
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- Apoptosis of Murine Macrophage-like Cells Infected with Orientia tsutsugamushi
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Choi NJ, Kim MK, Park HJ, Lim BU, Kang JS
- KMID: 2146930
- J Korean Soc Microbiol.
- 1998 Aug;33(4):399-406.
A large number of bacterial pathogens have been identified as mediators of apoptosis in vitro and the induction of apoptosis might be an important step in the pathogenesis of these... -
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- Protective Effects of Verapamil against H2O2-Induced Apoptosis in Human Lens Epithelial Cells
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Wang Z, Wang D, Li Y, Zhang X
- KMID: 2170598
- Biomol Ther.
- 2014 Nov;22(6):553-557.
- doi: 10.4062/biomolther.2014.033
Verapamil is used in the treatment of hypertension, angina pectoris, and atrial fibrillation. Recently, several studies have demonstrated that verapamil increased the optic nerve head blood flow and improved the... -
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- Pseudolaric acid B inhibits PAX2 expression through Wnt signaling and induces BAX expression, therefore promoting apoptosis in HeLa cervical cancer cells
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Guan D, Li C, Lv X, Yang Y
- KMID: 2457155
- J Gynecol Oncol.
- 2019 Sep;30(5):e77.
- doi: 10.3802/jgo.2019.30.e77
OBJECTIVES: Pseudolaric acid B (PAB) has been shown to inhibit the growth of various tumor cells, but the molecular details of its function are still unknown. This study investigated the... -
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- Cytotoxicity of COX-2 Inhibitor (Nimesulide) in Non-small Cell Lung Cancer Cell Line
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Park CB, Jeon HW, Jin U, Cho KD, Kim CK, Wang YP
- KMID: 1878439
- Korean J Thorac Cardiovasc Surg.
- 2005 Apr;38(4):263-270.
BACKGROUND: In recent years, a combination of two demographic phenomena, an increased number of older people in the population and an increase in the incidence of lung cancer with age,... -
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- Synergistic Effect of Parthenolide in Combination with 5-Fluorouracil in SW480 Cells
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Kim SL, Kieu TT, Jeon BJ, Kim SH, Kim IH, Lee SO, Lee ST, Kim SW
- KMID: 2174252
- Intest Res.
- 2012 Oct;10(4):357-364.
- doi: 10.5217/ir.2012.10.4.357
BACKGROUND/AIMS: Parthenolide (PT) is responsible for the bioactivities of Feverfew. Besides its potent anti-inflammatory effect, this compound has recently been reported to induce apoptosis in cancer cells. Unfortunately, many of... -
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- Phorbol Ester Induced - Apoptosis Mediated by Activating Serine Protease ( s ) and Caspase - 3 / CPP32 in SNU - 16 Human Gastric Cancer Cell Line
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Park IC, Park MJ, Choe TB, Jang JJ, Hong SI, Lee SH
- KMID: 2175097
- J Korean Cancer Assoc.
- 2000 Apr;32(2):270-278.
PURPOSE: Protein kinase C (PKC) is a family of phospholipid dependent serine/threonine protein kinases that have important role in differentiation, development and tumor promotion. PKC also has been reported to be implicated... -
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- Clusterin Expression and Apoptosis in Transitional Cell Carcinoma of the Bladder
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Park HJ, Lee HJ, Yum YH, Kang JY, Yoo TK
- KMID: 1997107
- Korean J Urol.
- 2007 Apr;48(4):402-407.
- doi: 10.4111/kju.2007.48.4.402
PURPOSE: The clusterin expression has been associated with tumorigenesis of various malignancies, including tumors of the prostate, colon and breast. Furthermore, the expression of clusterin is modulated by many factors... -
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- TGF-β1 upregulates the expression of hyaluronan synthase 2 and hyaluronan synthesis in culture models of equine articular chondrocytes
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Ongchai S, Somnoo O, Kongdang P, Peansukmanee S, Tangyuenyong S
- KMID: 2427021
- J Vet Sci.
- 2018 Nov;19(6):735-743.
- doi: 10.4142/jvs.2018.19.6.735
We investigated the effect of transforming growth factor beta 1 (TGF-β1) on equine hyaluronan synthase 2 (HAS2) gene expression and hyaluronan (HA) synthesis in culture models of articular chondrocytes. Equine... -
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- Role of p-38 MAP Kinase in apoptosis of hypoxia-induced osteoblasts
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Yoon JH, Jeong AJ, Kang KH, Kim SC
- KMID: 1976489
- Korean J Orthod.
- 2003 Jun;33(3):169-183.
Tooth movement by orthodontic force effects great tissue changes within the periodontium, especially by shifting the blood flow in the pressure side and resulting in a hypoxic state of low... -
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- Parthenogenetic Mouse Embryonic Stem Cells have Similar Characteristics to In Vitro Fertilization mES Cells
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Park SP, Kim EY, Lee KS, Lee YJ, Shin HA, Min HJ, Lee HT, Chung KS, Lim JH
- KMID: 1864601
- Korean J Fertil Steril.
- 2002 Jun;29(2):129-138.
OBJECTIVE: This study was to compare the characteristics between parthenogenetic mES (P-mES) cells and in vitro fertilization mES cells. MATERIAL AND METHODS: Mouse oocytes were recovered from superovulated 4 wks hybrid... -
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- Parthenolide Sensitizes Human Colorectal Cancer Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand through Mitochondrial and Caspase Dependent Pathway
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Trang KT, Kim SL, Park SB, Seo SY, Choi CH, Park JK, Moon JC, Lee ST, Kim SW
- KMID: 2174335
- Intest Res.
- 2014 Jan;12(1):34-41.
- doi: 10.5217/ir.2014.12.1.34
BACKGROUND/AIMS: Combination therapy utilizing tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in conjunction with other anticancer agents, is a promising strategy to overcome TRAIL resistance in malignant cells. Recently, parthenolide... -
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- Anti-carcinogenic actions of glycoprotein conjugated with isoflavones from submerged-liquid culture of Agaricus blazei mycelia through reciprocal expression of Bcl-2 and Bax proteins
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Kim YS, Kim BH, Kim GS, Jang JS, Kim SY, Choi BD, Kim JO, Ha YL
- KMID: 2169000
- J Biomed Res.
- 2014 Dec;15(4):200-206.
- doi: 10.12729/jbr.2014.15.4.200
Glycoproteins isolated from fruit bodies and mycelial cultures of mushrooms exhibit anti-carcinogenic actions in human cancer cells and animal tumor cells by induction of apoptosis. Here, we report that isoflavone-conjugated... -
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- Bleomycin Inhibits Proliferation via Schlafen-Mediated Cell Cycle Arrest in Mouse Alveolar Epithelial Cells
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Jang S, Ryu SM, Lee J, Lee H, Hong SH, Ha KS, Park WS, Han ET, Yang SR
- KMID: 2453983
- Tuberc Respir Dis.
- 2019 Apr;82(2):133-142.
- doi: 10.4046/trd.2017.0124
BACKGROUND: Idiopathic pulmonary fibrosis involves irreversible alveolar destruction. Although alveolar epithelial type II cells are key functional participants within the lung parenchyma, how epithelial cells are affected upon bleomycin (BLM)... -
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