- Korean Red Ginseng Tonic Extends Lifespan in D. melanogaster
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Kim MS
- KMID: 1502494
- Biomol Ther.
- 2013 May;21(3):241-245.
Aging is the single most important risk factor that increases susceptibility to many forms of diseases. As such, much effort has been put forward to elucidate the mechanisms behind the... -
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- DA-9701: A New Multi-Acting Drug for the Treatment of Functional Dyspepsia
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Kwon YS, Son M
- KMID: 1502485
- Biomol Ther.
- 2013 May;21(3):181-189.
Motilitone(R) (DA-9701) is a new herbal drug that was launched for the treatment of functional dyspepsia in December 2011 in Korea. The heterogeneous symptom pattern and multiple causes of functional... -
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- Administration of Phytoceramide Enhances Memory and Upregulates the Expression of pCREB and BDNF in Hippocampus of Mice
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Lee Y, Kim J, Jang S, Oh S
- KMID: 1502492
- Biomol Ther.
- 2013 May;21(3):229-233.
This study was aimed at investigating the possible effects of phytoceramide (Pcer) on learning and memory and their underlying mechanisms. Phytoceramide was orally administered to ICR mice for 7 days.... -
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- Protective Effect of Fisetin (3,7,3',4'-Tetrahydroxyflavone) against gamma-Irradiation-Induced Oxidative Stress and Cell Damage
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Piao MJ, Kim KC, Chae S, Keum YS, Kim HS, Hyun JW
- KMID: 1502489
- Biomol Ther.
- 2013 May;21(3):210-215.
Ionizing radiation can induce cellular oxidative stress through the generation of reactive oxygen species, resulting in cell damage and cell death. The aim of this study was to determine whether... -
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- Annexin A5 as a New Potential Biomarker for Cisplatin-Induced Toxicity in Human Kidney Epithelial Cells
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Kwon YJ, Jung JJ, Park NH, Ye DJ, Kim D, Moon A, Chun YJ
- KMID: 1502486
- Biomol Ther.
- 2013 May;21(3):190-195.
Cisplatin is a member of platinum-containing anti-cancer drugs that causes cross-linking of DNA and ultimately cancer cell apoptosis. The therapeutic function of cisplatin on various types of cancers has been... -
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- Transglutaminase-2 Is Involved in Expression of Osteoprotegerin in MG-63 Osteosarcoma Cells
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Lee HJ, Lee CH
- KMID: 1502488
- Biomol Ther.
- 2013 May;21(3):204-209.
Osteoprotegerin (OPG) is a secreted glycoprotein and a member of the tumor necrosis factor receptor superfamily. It usually functions in bone remodeling, by inhibiting osteoclastogenesis through interaction with a receptor... -
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- Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K
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Kim JH, Son YK, Kim GH, Hwang KH
- KMID: 1502493
- Biomol Ther.
- 2013 May;21(3):234-240.
Monoamine oxidase inhibitors (MAOI) have been widely used as antidepressants. Recently, there has been renewed interest in MAO inhibitors. The activity-guided fractionation of extracts from Angelica keiskei Koidzumi (A. keiskei... -
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- Chitin from the Extract of Cuttlebone Induces Acute Inflammation and Enhances MMP1 Expression
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Lee KM, Shim H, Lee GS, Park IH, Lee OS, Lim SC, Kang TJ
- KMID: 1502495
- Biomol Ther.
- 2013 May;21(3):246-250.
We previously reported that the extract from cuttlebone (CB) has wound healing effect in burned lesion of rat. In present study, the main component of CB extract was analyzed and... -
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- Aromadendrin Inhibits Lipopolysaccharide-Induced Nuclear Translocation of NF-kappaB and Phosphorylation of JNK in RAW 264.7 Macrophage Cells
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Lee JW, Kim NH, Kim JY, Park JH, Shin SY, Kwon YS, Lee HJ, Kim SS, Chun W
- KMID: 1502490
- Biomol Ther.
- 2013 May;21(3):216-221.
Aromadendrin, a flavonol, has been reported to possess a variety of pharmacological activities such as anti-inflammatory, antioxidant, and anti-diabetic properties. However, the underlying mechanism by which aromadendrin exerts its biological... -
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- Valproic Acid Regulates alpha-Synuclein Expression through JNK Pathway in Rat Primary Astrocytes
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Kim JN, Kim MK, Cho KS, Choi CS, Park SH, Yang SI, Joo SH, Park JH, Bahn G, Shin CY, Lee HJ, Han SH, Kwon KJ
- KMID: 1502491
- Biomol Ther.
- 2013 May;21(3):222-228.
Although the role of alpha-synuclein aggregation on Parkinson's disease is relatively well known, the physiological role and the regulatory mechanism governing the expression of alpha-synuclein are unclear yet. We recently... -
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- Modulation of Human Cardiac Progenitors via Hypoxia-ERK Circuit Improves their Functional Bioactivities
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Jung SY, Choi SH, Yoo SY, Baek SH, Kwon SM
- KMID: 1502487
- Biomol Ther.
- 2013 May;21(3):196-203.
Recent accumulating studies have reported that hypoxic preconditioning during ex vivo expansion enhanced the self-renewal or differentiation of various stem cells and provide an important strategy for the adequate modulation... -
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