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Drug Similarity Search Based on Combined Signatures in Gene Expression Profiles

Cha K, Kim MS, Oh K, Shin H, Yi GS

OBJECTIVES: Recently, comparison of drug responses on gene expression has been a major approach to identifying the functional similarity of drugs. Previous studies have mostly focused on a single feature,...
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Characterization of biological responses of colorectal cancer cells to anticancer regimens

Roh SA, Choi EY, Cho DH, Yoon YS, Kim TW, Kim YS, Kim JC

PURPOSE: Identification of subgroups of patients who differ in their response to treatment could help to establish which of the best available chemotherapeutic options are best, based on biological activity....
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Rapid Decrease of Intact Parathyroid Hormone Could Be a Predictor of Better Response to Cinacalcet in Hemodialysis Patients

Kim JK, Kwon YJ, Kim SW, Kim YH, Park CW, Choi KB, Hwang SD, Choi KH

PURPOSE: Cinacalcet is effective for treating refractory secondary hyperparathyroidism (SHPT), but little is known about the response rates and clinical factors influencing the response. MATERIALS AND METHODS: A prospective, single-arm, multi-center...
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