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Role of Sodium Ion in Renal Transport of p-Aminohippurate in vitro

Park YS, Lee SM

The effect of sodium on p-aminohippurate (PAH) transport kinetics was studied in isolated rat kidney slices in an attempt to define the role of sodium ion in renal organic acid...
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Radioiodine Therapy in Differentiated Thyroid Cancer: The First Targeted Therapy in Oncology

Chung JK, Cheon GJ

Iodide uptake across the membranes of thyroid follicular cells and cancer cells occurs through an active transport process mediated by the sodium-iodide symporter (NIS). The rat and human NIS-coding genes...
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Changes in Rena1 Na-K-ATPase Activity and PAH Transport Kinetics in Uninephrectomized Rats and Cold Exposed Hamsters

Park YS, Lee SM, Hwang AR

Renal Na+, K+-activated adenosinetriphosphatase (Na-K-ATPase) activity and the p-aminohippurate (PAH) transport kinetics were studied in uninephrectomized rats and cold exposed hamsters. In rats, the specific activity of renal Na-K-ATPase increased...
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Essential Corneal Edema

Kim HB, Lee SY, Lim DG

  • KMID: 1665764
  • J Korean Ophthalmol Soc.
  • 1980 Sep;21(3):313-315.
Normally the cornea has a water content varying between 76-78%, a state of relative dehydration maintained through its own metabolism by the active transport of water and ions across its...
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Effect of Carteolol Hydrochloride on Sodium-Potassium Activated ATPase in Cattle Lena Epithelial Cell Membrane

Lee KH, Chang WG, Kang BN

  • KMID: 2122943
  • J Korean Ophthalmol Soc.
  • 1990 Feb;31(2):207-213.
The effect of Carteolol hydrocholride on the Na-K ATPase of anterior capsule and epithelium of cattle lens has been investigated. The experiments were also designed to determine the action of...
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A Case of Congenital Chloridorrhea

Seo JL, Jung WC, Kim KT, Kim YS, Lee SW, Cho Y, Ro ES, Lee HJ

  • KMID: 2280492
  • Korean J Perinatol.
  • 1998 Mar;9(1):43-49.
Congenital chloridorrhea is a rare autosomal recessive disease and results from impairment of active transport of chloride in the ileum and colon. Absence of the Cl-/HCO3-, exchange pump causes polyhydramnios,...
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Variation of pH and Electrolyte in Nasal Secretum

Lee KD, Park HW, Ban YS, Choi BN, Park CY

  • KMID: 2074277
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 May;40(5):641-646.
BACKGROUND: Airway secretions partly arise from the interstitial fluid and partly from the secretory activities of respiratory epithelium and submucosal gland. The flow of water across the tracheobronchial epithelium is...
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Induction of apoptosis in human leukemia cells by 3-deazaadenosine is mediated by caspase-3-like activity

Kim HS, Jeong SY, Lee JH, Kim BE, Kim JW, Jeong SW, Kim IK

  • KMID: 755099
  • Exp Mol Med.
  • 2000 Dec;32(4):197-203.
3-Deazaadenosine (DZA), one of the potent inhibitors of S-adenosylhomocysteine hydrolase, is known to possess several biological properties including an induction of apoptosis. To evaluate a possibility that DZA...
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Transport of Tetraethylammonium in Renal Cortical Endosomes of Cadmium-Intoxicated Rats

Park HS, Kim KR, Park YS

  • KMID: 1614854
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):21-26.
Effects of cadmium (Cd) intoxication on renal endosomal accumulation of organic cations (OC ) were studied in rats using 14C-tetraethylammnium (TEA) as a substrate. Cd intoxication was induced by s.c....
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Can time delay be shortened in the treatment of acute myocardial infarction?: Experience from Korea acute myocardial infarction registry

Jeong MH

  • KMID: 2259136
  • Korean J Med.
  • 2010 May;78(5):582-585.
Time delay between medial contact and treatment in symptomatic patients with acute myocardial infarction (AMI) is the most important factor in the prediction of short and long-term mortality. The incidences...
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A Study of Localization of Alkaline Phosphatase Activity in Endometrium of Mouse Uterus During Estrous Cycle

Kim SR, Kim MK

This study has been done in order to verify the localization of alkaline phosphatase(ALP) activity, in connection with the mechanism of seceretion and absorption of luminal fluid in the mouse...
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Sodium Iodide Symporter and the Radioiodine Treatment of Thyroid Carcinoma

Chung JK, Youn HW, Kang JH, Lee HY, Kang KW

  • KMID: 2051960
  • Nucl Med Mol Imaging.
  • 2010 Apr;44(1):4-14.
Since the specific accumulation of iodide in thyroid was found in 1915, radioiodine has been widely applied to diagnose and treat thyroid cancer. Iodide uptake occurs across the membrane of...
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Biochemical Characteristics of The Na-alpha-Ketoglutarate Cotransport System in Proximal Convoluted and Straight Tubules of the Rabbit Kidney

Ahn DW, Kim KR, Park HS, Park YS

  • KMID: 2254125
  • Korean J Nephrol.
  • 2007 Jan;26(1):5-13.
PURPOSE: alpha-Ketoglutarate (alphaKG), a Krebs cycle intermediate, is extensively used in the kidney as a fuel substrate and as a counter anion for organic acid secretion. It is known to...
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Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney

Kwak JO, Kim HW, Oh KJ, Kim DS, Han KO, Cha SH

  • KMID: 1056233
  • Exp Mol Med.
  • 2005 Jun;37(3):204-212.
The organic anion transporters (OAT) have recently been identified. Although the some transport properties of OATs in the kidney have been verified, the regulatory mechanisms for OAT's functions are still...
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The Changes in Serum and Cerebrospinal Fluid Ca2+, Mg2+, and Ca2+/Mg2+ Ratio in Neuropathic Rats

Jeong SM, Park CH, Shin JW, Lim JG, Lee C, Han SM

BACKGROUND: Central sensitization of neuropathic pain is associated with an influx of extracellular calcium via the opening of N-methyl-D-aspartate (NMDA) receptor-gated ion channels, which is usually blocked by a magnesium...
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Enhanced Effect of Iodide - Uptake in Thyroid Carcinoma Cells by Infecting Adenovirus - Human Sodium Iodide Symporter (Ad - hNIS)

Park KK, Jin JS, Lee SJ, Park JY, Lee HR, Moon DH, Ahn IM, Chang HS

  • KMID: 2199730
  • J Korean Soc Endocrinol.
  • 2000 Oct;15(4-5):522-531.
BACKGROUND: The sodium-iodide-symporter (NIS) is a plasma membrane glycoprotein with 13 putative transmembrane domains, which is responsible for concentrating iodide into the thyroid by an active transport and provides the...
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The Effect of Salt on Serum Glycemic Response and Gastric Emptying after Oral Glucose Loading

Kim JM, Park JH, Kim MS, Kim JY, Kim YJ, Lee DB, Yang SW, Jin DJ, Chung MY, Lee TH

  • KMID: 2275024
  • Chonnam Med J.
  • 1997 Dec;33(2):163-170.
When studied in vitro, active transport of glucose across the intestinal mucosa is absolutely dependent upon the presence of sodium in the gut lumen, the role of intraluminal sodium in...
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Ultrastructure and blood-iris barrier in experimental rubeosis iridis in rabbit

Ko MK, Park LW, Kim YJ, Choe JK

Iris neovascularization was produced in rabbits by hypotony following repeated aspiration of the vitreous. The hypotony was produced after 0.3 ml of vitreous fluid was aspirated using a 25-gauge needle...
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Mechanisms of Antiepileptic Drugs

Kim JM

  • KMID: 1816473
  • J Korean Epilepsy Soc.
  • 2000 Dec;4(2):108-118.
Established antiepileptic drugs (AEDs) decrease membrane excitability by interacting with neurotransmitter receptors or ion channels. AEDs developed prior to 1980 appear to act on sodium channels, gamma-amino butyric acid type...
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