- Hypoxia Activates Toll-like Receptor 4 Signaling in Primary Mouse Hepatocytes Through the Receptor Clustering within Lipid Rafts
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Kim DH, Billiar TR
- KMID: 1963583
- J Korean Surg Soc.
- 2011 Mar;80(3):194-203.
- doi: 10.4174/jkss.2011.80.3.194
PURPOSE: Transient hypoxia is an initial event that accentuates ischemia/reperfusion (I/R) injury in the liver. Hepatic ischemia/reperfusion (I/R) injury is largely related to innate immunity via Toll-like receptor 4 (TLR4)... -
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- Nitric oxide suppresses inducible nitric oxide synthase expression by inhibiting post-translational modification of I kappa B
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Chang K, Lee SJ, Cheong I, Billiar TR, Chung HT, Han JA, Kwon YG, Ha KS, Kim YM
- KMID: 1094075
- Exp Mol Med.
- 2004 Aug;36(4):311-324.
The expression of inducible nitric oxide synthase (iNOS) is a critical factor in both normal physiological functions and the pathogenesis of disease. This study was undertaken to determine the molecular... -
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