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Immunohistochemical Study of p53 Mutation and p16, p14 Alterations Encoded by INK4a-ARF in Mucin-ypersecreting Bile Duct Tumor

Kim HJ, Kim MH, Song MH, Song DE, Yu E

  • KMID: 1767495
  • Korean J Gastroenterol.
  • 2005 Mar;45(3):189-194.
BACKGROUND/AIMS: Mucin-hypersecreting bile duct tumor is rare, and has an unusual histologic characteristic of having various degrees of cellular atypia ranging from dysplasia to invasive carcinoma in the same specimen....
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Frequency of Loss of Heterozygosity on Chromosome 17 in Intrahepatic Cholangiocarcinoma

Kim HJ, Kang CD, Lee SJ, Cho SJ, Kim JS

  • KMID: 782762
  • Korean J Gastroenterol.
  • 2006 Sep;48(3):188-194.
BACKGROUND/AIMS: Intrahepatic cholangiocarcinoma is the second most common intrahepatic neoplasm. Carcinogenesis is believed to be a multistage process that occurs as a result of mutations in oncogenes and tumor suppressor...
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Genetic Alterations in Intrahepatic Cholangiocarcinoma as revealed by Degenerate Oligonucleotide Primed PCR-Comparative Genomic Hybridization

Lee JY, Park YN, Uhm KO, Park SY, Park SH

Intrahepatic cholangiocarcinoma (ICC), a malignant neoplasm of the biliary epithelium, is usually fatal because of difficulty in early diagnosis and lack of availability of effective therapy. The genetic mechanisms involved...
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