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The Effect of Itopride Hydrochloride on the Gastrointestinal Motility in Postoperative Ileus of Guinea Pigs

Lim HC, Chon NR, Choi EJ, Lee YH, Lee MG, Park H

  • KMID: 2307441
  • Korean J Neurogastroenterol Motil.
  • 2008 Jun;14(1):18-23.
BACKGROUNDS/AIM: Postoperative ileus (POI) is characterized by a transiently impaired propulsive function of the entire gastrointestinal tract which results from activated inhibitory sympathetic neural reflexes in the gut after abdominal...
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Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro

Lim HC, Kim YG, Lim JH, Kim HS, Park H

PURPOSE: Itopride hydrochloride (itopride) inhibits acetylcholinesterase (AChE) and antagonizes dopamine D(2) receptor, and has been used as a gastroprokinetic agent. However, its prokinetic effect on the small bowel or colon...
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zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells

Yee SB, Baek SJ, Park HT, Jeong SH, Jeong JH, Kim TH, Kim JM, Jeong BK, Park BS, Kwon TK, Yoon I, Yoo YH

  • KMID: 1115941
  • Exp Mol Med.
  • 2006 Dec;38(6):634-642.
In a preliminary study, we found that benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone (zVAD- fmk), unlike Boc-aspartyl(OMe)-fluoromethylketone (BocD-fmk), at usual dosage could not prevent genistein-induced apoptosis of p815 mastocytoma cells. This study was undertaken to...
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