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Impact of Lysophosphatidylcholine on the Plasminogen Activator System in Cultured Vascular Smooth Muscle Cells

Yoon BK, Kang YH, Oh WJ, Park K, Lee DY, Choi D, Kim DK, Lee Y, Rhyu MR

The balance between tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) regulates fibrinolysis. PAI-1 expression increases in atherosclerotic arteries and vascular smooth muscle cells (VSMCs) are one...
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In vivo alternative testing with zebrafish in ecotoxicology

Seok SH, Baek MW, Lee HY, Kim DJ, Na YR, Noh KJ, Park SH, Lee HK, Lee BH, Park JH

Although rodents have previously been used in ecotoxicological studies, they are expensive, time-consuming, and are limited by strict legal restrictions. The present study used a zebrafish (Danio rerio) model and...
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