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Tolvaptan: a possible preemptive treatment option in children with autosomal dominant polycystic kidney disease?

Beak HS, Cho MH

Tolvaptan is a highly selective vasopressin receptor 2 antagonist that regulates cyclic adenosine monophosphate levels to inhibit both epithelial cell proliferation and chloride ion excretion, two mechanisms known to induce...
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