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Analysis of the Vaginal Microbiome by Next-Generation Sequencing and Evaluation of its Performance as a Clinical Diagnostic Tool in Vaginitis

Hong KH, Hong SK, Cho SI, Ra E, Han KH, Kang SB, Kim EC, Park SS, Seong MW

BACKGROUND: Next-generation sequencing (NGS) can detect many more microorganisms of a microbiome than traditional methods. This study aimed to analyze the vaginal microbiomes of Korean women by using NGS that...
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Molecular characterization of bacterial endosymbionts of Acanthamoeba isolates from infected corneas of Korean patients

Xuan YH, Yu HS, Jeong HJ, Seol SY, Chung DI, Kong HH

The endosymbionts of 4 strains of Acanthamoeba (KA/E9, KA/E21, KA/E22, and KA/E23) isolated from the infected corneas of Korean patients were characterized via orcein stain, transmission electron microscopic examination, and...
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Rapid Clinical Bacteriology and Its Future Impact

van Belkum A, Durand G, Peyret M, Chatellier S, Zambardi G, Schrenzel , Shortridge D, Engelhardt A, Dunne WM

Clinical microbiology has always been a slowly evolving and conservative science. The sub-field of bacteriology has been and still is dominated for over a century by culture-based technologies. The integration...
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