- Impaired phosphorylation and mis-localization of Bub1 and BubR1 are responsible for the defective mitotic checkpoint function in Brca2-mutant thymic lymphomas
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Lee H
- KMID: 1093618
- Exp Mol Med.
- 2003 Oct;35(5):448-453.
Breast cancer susceptibility gene, BRCA2, is a tumor suppressor and individuals who inherit one defected copy of BRCA2 allele experience early onset breast cancer or ovarian cancer accompanied by the... -
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- Comparison of Targeted Next-Generation and Sanger Sequencing for the BRCA1 and BRCA2 Mutation Screening
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Park J, Jang W, Chae H, Kim Y, Chi HY, Kim M
- KMID: 2373527
- Ann Lab Med.
- 2016 Mar;36(2):197-201.
- doi: 10.3343/alm.2016.36.2.197
No abstract available. -
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- Conditional knockout of brca1/2 and p53 in mouse ovarian surface epithelium: Do they play a role in ovarian carcinogenesis?
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Kim KY, Park DW, Jeung EB, Choi KC
- KMID: 1072177
- J Vet Sci.
- 2010 Dec;11(4):291-297.
- doi: 10.4142/jvs.2010.11.4.291
Alterations of genes are known to be critical for the induction of tumorigenesis, but the mechanism of ovarian carcinogenesis is little understood and remains to be elucidated. In this study,... -
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- Young Israeli women with epithelial ovarian cancer: prevalence of BRCA mutations and clinical correlates
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Helpman L, Zidan O, Friedman E, Kalfon S, Perri T, Ben-Baruch G, Korach J
- KMID: 2413221
- J Gynecol Oncol.
- 2017 Sep;28(5):e61.
- doi: 10.3802/jgo.2017.28.e61
OBJECTIVE: The current study investigates disease patterns and outcomes in young Israeli epithelial ovarian cancer (EOC) patients and their association with BRCA mutation status. METHODS: Consecutive EOC patients diagnosed at or... -
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- Prevalence of BRCA1 and BRCA2 Mutations in Korean Breast Cancer Patients
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Ahn SH, Hwang UK, Kwak BS, Yoon HS, Ku BK, Kang HJ, Kim JS, Ko BK, Ko CD, Yoon KS, Cho DY, Kim JS, Son BH
- KMID: 1733488
- J Korean Med Sci.
- 2004 Apr;19(2):269-274.
- doi: 10.3346/jkms.2004.19.2.269
The incidence of breast cancer in Korea has been increasing in recent years, such that it is now the most common female cancer. Breast cancer in Korea is characterized by... -
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