- The CD28-B7 Family in Anti-Tumor Immunity: Emerging Concepts in Cancer Immunotherapy
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Leung J, Suh WK
- KMID: 2150817
- Immune Netw.
- 2014 Dec;14(6):265-276.
- doi: 10.4110/in.2014.14.6.265
The interactions between B7 molecules and CD28-family receptors are crucial in the regulation of adaptive cellular immunity. In cancer, the aberrant expression of co-inhibitory B7 molecules has been attributed to... -
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- miR-195/miR-497 Regulate CD274 Expression of Immune Regulatory Ligands in Triple-Negative Breast Cancer
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Yang L, Cai Y, Zhang D, Sun J, Xu C, Zhao W, Jiang W, Pan C
- KMID: 2429815
- J Breast Cancer.
- 2018 Dec;21(4):371-381.
- doi: 10.4048/jbc.2018.21.e60
PURPOSE: Immune suppression is common in patients with advanced breast cancer but the mechanisms underlying this phenomenon have not been sufficiently studied. In this study, we aimed to identify B7... -
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- Immunotherapeutic Effects of CTLA4Ig Fusion Protein on Murine EAE and GVHD
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Jang SO, Hong SJ, Cho HS, Chung YH
- KMID: 2054235
- Immune Netw.
- 2003 Dec;3(4):302-309.
- doi: 10.4110/in.2003.3.4.302
BACKGROUND: CTLA4 (CD152), which is expressed on the surface of T cells following activation, has a much higher affinity for B7 molecules comparing to CD28, and is a negative regulator... -
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