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Determination of Minimum Inhibitory Concentrations of Several Azole Antifungals for Malassezia furfur

Ahn KJ, Ashbee HR

BACKGROUND: There have been several reports which assessed the activity of antifungals including azoles on Malassezia furfur by agar dilution method. However, they did not differentiate M. furfur into groups....
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Identification and Functional Characterization of a Cryptococcus neoformans UPC2 Homolog

Kim NK, Han K, Jung WH

Azoles are currently the most widely used class of antifungal drugs clinically, and are effective for treating fungal infections. Target site of azoles is ergosterol biosynthesis in fungal cell membrane,...
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Antifungal Resistance in Yeasts and Filamentous Fungi

Shin JH

The incidence of invasive fungal infection has increased worldwide along with the increasing population of high risk patients. Recently developed antifungal agents, such as second-generation triazoles and echinocandins, provide the...
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Susceptibilities to Azoles of Candida albicans in Vulvovaginal Candidiasis

Kim KH, Kim TH, Lee MK

  • KMID: 1449502
  • Korean J Med Mycol.
  • 2011 Mar;16(1):24-30.
BACKGROUND: There are limited data regarding the antifungal susceptibility of Candida albicans causing recurrent vulvovaginal candidiasis. OBJECTIVE: The aim of the present study was to evaluate the effect of azoles susceptibilities...
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Species Distribution and Susceptibilities to Azoles of Candida Species Including C. tropicalis in a Tertiary Burn Center

Kim TH, Lee YS, Lee MK, Lee KM

BACKGROUND: Candida species are the fourth leading cause of nosocomial bloodstream infections and have one of the highest mortality rates among nosocomial pathogens. C. tropicalis has been reported to be...
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A Case of Psoas Abscess Caused by Candida glabrata

Kim M, Lee J, Chung CS, Jang JH, Ahn BM, Song W

Infections due to Candida species are becoming more frequent in several patient population and settings. The proportion of non-albicans Candida spp. causing candidemia has increased during the recent decades. Especially,...
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In Vitro Susceptibilities to Caspofungin and Micafungin of Clinical Isolates of Candida Species

Choi HW, Shin JH, Lee JS, Cho D, Shin MG, Suh SP, Ryang DW

BACKGROUND: Caspofungin and micafungin are echinochandins with potent activities against Candida species. However, in vitro susceptibility to these agents of clinical Candida isolates in Korea has not been fully surveyed....
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In vitro Evaluation of Antibiotic Lock Technique for the Treatment of Candida albicans, C. glabrata, and C. tropicalis Biofilms

Ko KS, Lee JY, Song JH, Peck KR

Candidaemia associated with intravascular catheter-associated infections is of great concern due to the resulting high morbidity and mortality. The antibiotic lock technique (ALT) was previously introduced to treat catheter-associated bacterial...
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The Optimal Wavelength of Spectrophotometric Broth Microdilution Antifungal Susceptibility Test for Flucytosine and Three Azoles

Lee JY, Lee EJ, Kim SH, Jeong HS, Oh SH, Kim HR, Lee JN, Chang CL, Kho WG, Shin JH

BACKGROUND: There is no guideline for the appropriate wavelength at which to measure the optical density (OD) value in broth microdilution antifungal susceptibility testing, although a spectrophotometric reading method is...
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Species-Specific Differences in Rhodamine 6G Accumulation of Candida Isolates Detected by Flow Cytometric Analysis

Moon CJ, Shin JH, Kim DW, Kee SJ, Kim SH, Shin MG, Suh SP, Ryang DW

BACKGROUND: Fluorescent dye Rhodamine 6G (R6G) is a substrate of multidrug resistance pumps and its accumulation is reduced in some azole-resistant Candida isolates with the upregulation of multidrug efflux transporter...
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Species Distribution and Susceptibility to Azole Antifungals of Candida Bloodstream Isolates from Eight University Hospitals in Korea

Lee JS, Shin JH, Lee K, Kim MN, Shin BM, Uh Y, Lee WG, Lee HS, Chang CL, Kim SH, Shin MG, Suh SP, Ryang DW

PURPOSE: The incidence of Candida bloodstream infections (BSI) has increased over the past two decades. The rank order of occurrence and the susceptibility to antifungals of the various Candida...
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