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Comparison of time until elective intestinal resection regarding previous anti-tumor necrosis factor exposure: a Brazilian study on patients with Crohn's disease

Kotze PG, Magro DO, Saab B, Saab MP, Pinheiro L, Olandoski , Ayrizono M, Martinez C, Coy CS

BACKGROUND/AIMS: The use of anti-tumor necrosis factor (anti-TNF) agents seems to reduce surgical rates and delay surgical procedures in prospective trials and population-based studies in the management of Crohn's disease...
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Changes in serum levels of lipopolysaccharides and CD26 in patients with Crohn's disease

Magro DO, Kotze PG, Martinez C, Camargo MG, Guadagnini D, Calixto AR, Vasques AC, Ayrizono M, Geloneze B, Pareja JC, Saad MJ, Coy CS

BACKGROUND/AIMS: Lipopolysaccharide (LPS) is a molecule formed by lipids and polysaccharides and is the major cell wall component of gram-negative bacteria. High LPS levels are known to block CD26 expression...
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