- Immunohistochemical characterization of the cellular infiltrate in airway mucosa of toluene diisocyanate (TDI)-induced asthma: comparison with allergic asthma
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Park HS, Hwang SC, Nahm DH, Yim HE
- KMID: 1107221
- J Korean Med Sci.
- 1998 Feb;13(1):21-26.
- doi: 10.3346/jkms.1998.13.1.21
Toluene diisocyanate (TDI) is the most prevalent agent in occupational asthma (OA) in Korea. The immuno-pathologic mechanism for TDI-induced bronchoconstriction remains to be clarified. We studied the immunohistochemical finding of... -
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- Presence of circulating autoantibodies against bronchial epithelia cell in patients with nonatopic asthma
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Nahm DH, Yim H, Lee HJ, Yim EJ, Choi EA, Kim SS, Lee SK, Park HS
- KMID: 2157542
- J Korean Med Sci.
- 2000 Dec;15(6):631-634.
- doi: 10.3346/jkms.2000.15.6.631
Allergic response to common environmental agents has been regarded as a main pathogenetic mechanism of bronchial asthma. However, allergic sensitization (atopy) can not be detected in a siginificant number of... -
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- Endotoxin and House Dust Mite Allergen Levels on Synthetic and Buckwheat Pillows
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Nam HS, Park CS, Crane J, Siebers R
- KMID: 2157676
- J Korean Med Sci.
- 2004 Aug;19(4):505-508.
- doi: 10.3346/jkms.2004.19.4.505
Pillows are known to contain significant levels of indoor allergens and endotoxin, that are of importance to house dust mite sensitized asthmatics. Buckwheat pillows are commonly used in Korea. We... -
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- Cytokine secretion patterns of T cells responding to haptenized-human serum albumin in toluene diisocyanate (TDI)-induced asthma patients
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Lee M, Park S, Park HS, Youn JK
- KMID: 645203
- J Korean Med Sci.
- 1998 Oct;13(5):459-465.
- doi: 10.3346/jkms.1998.13.5.459
Our understanding immune response mechanisms to chemical allergens has been limited. It was partly due to the nature of antigens, recognized by T cells, not being well characterized. In... -
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- Heterogeneity of IgE response to TDI-HSA conjugates by ELISA in toluene diisocyanate (TDI) -induced occupational asthma (OA) patients
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Son M, Lee M, Kim YT, Youn JK, Park H
- KMID: 1064961
- J Korean Med Sci.
- 1998 Apr;13(2):147-152.
- doi: 10.3346/jkms.1998.13.2.147
Toluene diisocyanate (TDI), a low molecular weight reactive chemical, is known to be a main cause of occupational asthma (OA) in Korea. Although it is thought that inhaled TDI... -
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- BCG infection during pre-sensitization or even post-sensitization inhibits airway sensitivity in an animal model of allergic asthma
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Koh YI, Choi IS, Park SC, Kang KW
- KMID: 1128622
- J Korean Med Sci.
- 2000 Jun;15(3):265-272.
- doi: 10.3346/jkms.2000.15.3.265
The objective of this study is to investigate whether BCG infection before, during or after sensitization suppresses allergen-induced airway hyperresponsiveness and eosinophilic inflammation in allergic asthma rats, and to determine... -
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- Recent Advances in Mechanisms and Treatments of Airway Remodeling in Asthma: A Message from the Bench Side to the Clinic
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Cho JY
- KMID: 1729239
- Korean J Intern Med.
- 2011 Dec;26(4):367-383.
- doi: 10.3904/kjim.2011.26.4.367
Airway remodeling in asthma is a result of persistent inflammation and epithelial damage in response to repetitive injury. Recent studies have identified several important mediators associated with airway remodeling in... -
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- Role of circulating immune complex in aspirin-sensitive asthma
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Park HS, Nahm DH
- KMID: 759054
- Korean J Intern Med.
- 1998 Feb;13(1):51-55.
BACKGROUND & OBJECTIVES: The pathogenic mechanism of aspirin-sensitive asthma (ASA-BA) remains to be further defined. To evaluate the role of circulating immune complex (CIC) in ASA-BA. SUBJECTS & METHODS: We... -
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- Occupational asthma and IgE sensitization to grain dust
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Park HS, Nahm DH, Suh CH, Kwon OY, Kim KS, Lee SW, Chung HK
- KMID: 1745549
- J Korean Med Sci.
- 1998 Jun;13(3):275-280.
- doi: 10.3346/jkms.1998.13.3.275
To evaluate type I hypersensitivity to grain dust (GD), its prevalence and relationship to respiratory dysfunction, we studied clinical and immunologic features, including skin prick tests (SPT), serum specific... -
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- Diverse profiles of specific IgE response to toluene diisocyanate (TDI)-human serum albumin conjugate in TDI-induced asthma patients
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Park HS, Kim HY, Lee SK, Kim SS, Nahm DH
- KMID: 1066495
- J Korean Med Sci.
- 2001 Feb;16(1):57-61.
- doi: 10.3346/jkms.2001.16.1.57
The prevalence studies on specific IgE to toluene diisocyanate (TDI)-human serum albumin (HSA) conjugate in TDI-induced asthma have shown variable results. In this study, we attempted to compare specific IgE... -
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- Effects of prednisolone on eosinophils, IL-5, eosinophil cationic protein, EG2+ eosinophils, and nitric oxide metabolites in the sputum of patients with exacerbated asthma
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Jang AS, Choi IS, Koh YI, Jeong TK, Lee KY, Kim YS, Lee JU, Park CS
- KMID: 965873
- J Korean Med Sci.
- 2000 Oct;15(5):521-528.
- doi: 10.3346/jkms.2000.15.5.521
Corticosteroids are considered to be one of the most effective medicine for asthma by suppressing airway inflammation. This study was carried out to investigate the effects of prednisolone in the... -
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- IgE binding patterns to German cockroach whole body extract in Korean atopic asthmatic children
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Lee SY, Lee DS, Kim KE, Jeaung BJ, Lee KY
- KMID: 711577
- Yonsei Med J.
- 1998 Oct;39(5):409-416.
- doi: 10.3349/ymj.1998.39.5.409
It is widely known that the cockroach is an inhalant allergen in atopic asthma and allergic rhinitis. Even though Bla g I and Bla g II are considered as the... -
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- Specific IgG1 and IgG4 antibodies to citrus red mite in citrus farmers: a study of their relationship to respiratory symptoms
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Park HS, Kim HY, Kim YK, Son JW, Nahm DH, Cho SH, Min KU, Kim YY
- KMID: 1730636
- J Korean Med Sci.
- 2000 Aug;15(4):407-412.
- doi: 10.3346/jkms.2000.15.4.407
Citrus red mite (CRM) is known as the most common sensitizing allergen in subjects with asthma and rhinitis working on citrus farms. The aim of this study is to evaluate... -
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- Prevalence of Soy Protein Hypersensitivity in Cow's Milk Protein-Sensitive Children in Korea
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Ahn KM, Han YS, Nam SY, Park HY, Shin MY, Lee SI
- KMID: 648895
- J Korean Med Sci.
- 2003 Aug;18(4):473-477.
- doi: 10.3346/jkms.2003.18.4.473
This study was aimed to evaluate the prevalence of soy protein hypersensitivity in cow's milk protein-sensitive children in Korea. A total of 1,363 patients with atopic dermatitis, urticaria, enterocolitis syndrome,... -
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- Comparison of basophil histamine releasability between atopic and nonatopic thmatics
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Son JW, Kim YK, Chung JW, Lee SR, Cho SH, Min KU, Koh YY, Kim YY
- KMID: 648073
- J Korean Med Sci.
- 1999 Apr;14(2):153-158.
- doi: 10.3346/jkms.1999.14.2.153
To compare the mediator releasability between atopic and nonatopic asthmatics, we measured basophil histamine releasability (BaHR) using a calcium-ionophore A23187 and anti-IgE in 137 subjects who were treated at Seoul... -
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- Exposure to Toluene Diisocyanate (TDI) Induces IL-8 Production from Bronchial Epithelial Cells: Effect of Pro-inflammatory Cytokines
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Lee YM, Kim HA, Park HS, Lee SK, Nahm DH
- KMID: 1086736
- J Korean Med Sci.
- 2003 Dec;18(6):809-812.
- doi: 10.3346/jkms.2003.18.6.809
This investigation was designed to confirm IL-8 production from human bronchial epithelial cells with toluene diisocyanate (TDI) exposure and to examine the effects of pro-inflammatory cytokine and dexamethasone. We cultured... -
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- Role of specific IgE, IgG and IgG4 antibodies to corn dust in exposed workers
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Park HS, Nahm DH, Kim HY, Suh CH, Kim KS
- KMID: 759074
- Korean J Intern Med.
- 1998 Jul;13(2):88-94.
BACKGROUND AND METHODS: To evaluate the role of specific antibodies to corn dust (CD) and their relationship to respiratory dysfunction, we detected serum specific IgE(slgE) and IgG4(slgG4) antibodies by ELISA... -
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