- Occupational asthma and IgE antibodies to reactive dyes
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Park HS, Kim YJ, Lee MK, Hong CS
- KMID: 1097021
- Yonsei Med J.
- 1989 Sep;30(3):298-304.
- doi: 10.3349/ymj.1989.30.3.298
Reactive dyes have been widely used in recent years. This paper reports nine cases of immediate type occupational asthma to reactive dyes in one dye industry. All patients had... -
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- Immunohistochemical characterization of the cellular infiltrate in airway mucosa of toluene diisocyanate (TDI)-induced asthma: comparison with allergic asthma
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Park HS, Hwang SC, Nahm DH, Yim HE
- KMID: 1107221
- J Korean Med Sci.
- 1998 Feb;13(1):21-26.
- doi: 10.3346/jkms.1998.13.1.21
Toluene diisocyanate (TDI) is the most prevalent agent in occupational asthma (OA) in Korea. The immuno-pathologic mechanism for TDI-induced bronchoconstriction remains to be clarified. We studied the immunohistochemical finding of... -
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- Increased neutrophil chemotactic activity is noted in alminum-induced occupational asthma
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Park HS, Uh ST, Park CS
- KMID: 1038465
- Korean J Intern Med.
- 1996 Jan;11(1):69-73.
A worker with occupational exposure to aluminum powder developed asthmatic symptoms three years and six months after starting work. Skin tests (prick and intradermal) to aluminum chloride (AlCl3) were negative.... -
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- Time Sequence of Airway Remodeling in a Mouse Model of Chronic Asthma: the Relation with Airway Hyperresponsiveness
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Kim SJ, Kim CH, Ahn JH, Kim MS, Kim SC, Lee SY, Kwon SS, Kim YK, Kim KH, Moon HS, Song JS, Park SH
- KMID: 1713158
- J Korean Med Sci.
- 2007 Apr;22(2):183-191.
- doi: 10.3346/jkms.2007.22.2.183
During the course of establishing an animal model of chronic asthma, we tried to elucidate the time sequence of airway hyperresponsiveness (AHR), airway inflammation, airway remodeling, and associated cytokines. Seven-week-old... -
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- Cytokeratin Autoantibodies: Useful Serologic Markers for Toluene Diisocyanate-Induced Asthma
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Ye YM, Nahm DH, Kim CW, Kim HR, Hong CS, Park CS, Suh CH, Park HS
- KMID: 1777164
- Yonsei Med J.
- 2006 Dec;47(6):773-781.
- doi: 10.3349/ymj.2006.47.6.773
To evaluate the clinical significance of autoantibodies to three major epithelial cytokeratins (CK) -- CK8, CK18, and CK19 -- we compared 66 patients with toluene diisocyanate (TDI)-induced asthma (group I)... -
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- Isocyanate-induced occupational asthma: challenge and immunologic studies
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Park HS, Nahm DH
- KMID: 1123814
- J Korean Med Sci.
- 1996 Aug;11(4):314-318.
- doi: 10.3346/jkms.1996.11.4.314
Isocyanate is the most prevalent agent in occupational asthma(OA) in Korea. We analyzed 43 toluene diisocyanate(TDI) induced OA patients of whom 81% were found to be spray painters. The bronchial... -
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- Cytokine secretion patterns of T cells responding to haptenized-human serum albumin in toluene diisocyanate (TDI)-induced asthma patients
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Lee M, Park S, Park HS, Youn JK
- KMID: 645203
- J Korean Med Sci.
- 1998 Oct;13(5):459-465.
- doi: 10.3346/jkms.1998.13.5.459
Our understanding immune response mechanisms to chemical allergens has been limited. It was partly due to the nature of antigens, recognized by T cells, not being well characterized. In... -
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- TACI:Fc scavenging B cell activating factor (BAFF) alleviates ovalbumin-induced bronchial asthma in mice
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Moon EY, Ryu SK
- KMID: 1047085
- Exp Mol Med.
- 2007 Jun;39(3):343-352.
Asthma was induced by the sensitization and challenge with ovalbumin (OVA) in mice. B-cell activating factor (BAFF) plays a role in mature B cell generation and maintenance. Here, we investigated... -
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- Diverse profiles of specific IgE response to toluene diisocyanate (TDI)-human serum albumin conjugate in TDI-induced asthma patients
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Park HS, Kim HY, Lee SK, Kim SS, Nahm DH
- KMID: 1066495
- J Korean Med Sci.
- 2001 Feb;16(1):57-61.
- doi: 10.3346/jkms.2001.16.1.57
The prevalence studies on specific IgE to toluene diisocyanate (TDI)-human serum albumin (HSA) conjugate in TDI-induced asthma have shown variable results. In this study, we attempted to compare specific IgE... -
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- Effect of intranasal rosiglitazone on airway inflammation and remodeling in a murine model of chronic asthma
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Lee HY, Rhee CK, Kang JY, Park CK, Lee SY, Kwon SS, Kim YK, Yoon HK
- KMID: 2373777
- Korean J Intern Med.
- 2016 Jan;31(1):89-97.
- doi: 10.3904/kjim.2016.31.1.89
BACKGROUND/AIMS: Asthma is characterized by airway hyperresponsiveness, inflammation, and remodeling. Peroxisome proliferator-activated receptors have been reported to regulate inflammatory responses in many cells. In this study, we examined the effects... -
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- Association between Recent Acetaminophen Use and Asthma: Modification by Polymorphism at TLR4
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Lee SH, Kang MJ, Yu HS, Hong K, Jung YH, Kim HY, Seo JH, Kwon JW, Kim BJ, Kim HJ, Kim YJ, Kim HS, Kim HB, Park KS, Lee SY, Hong SJ
- KMID: 1786107
- J Korean Med Sci.
- 2014 May;29(5):662-668.
- doi: 10.3346/jkms.2014.29.5.662
The risk of asthma has been increasing in parallel with use of acetaminophen, which is a potential source of oxidative stress. Toll-like receptor 4 (TLR4) plays a critical role not... -
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- Silencing IL-23 expression by a small hairpin RNA protects against asthma in mice
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Li Y, Sun M, Cheng H, Li S, Liu L, Qiao H, Hua S, Lu J
- KMID: 1104389
- Exp Mol Med.
- 2011 Apr;43(4):197-204.
- doi: 10.3858/emm.2011.43.4.024
To determine the impact of IL-23 knockdown by RNA interference on the development and severity of ovalbumin (OVA)-induced asthmatic inflammation, and the potential mechanisms in mice, the IL-23-specific RNAi-expressing pSRZsi-IL-23p19... -
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- Near-Road Exposure and Impact of Air Pollution on Allergic Diseases in Elementary School Children: A Cross-Sectional Study
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Kim HH, Lee CS, Yu SD, Lee JS, Chang JY, Jeon JM, Son HR, Park CJ, Shin DC, Lim YW
- KMID: 2374091
- Yonsei Med J.
- 2016 May;57(3):698-713.
- doi: 10.3349/ymj.2016.57.3.698
PURPOSE: The study aims to classify schools based on traffic pollutants and their complex sources, to assess the environment, to determine the state of allergic diseases among students using the... -
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- Enhanced Serum Neutrophil Chemotactic Activity was Noted in Both Early and Late Asthmatic Responses During Lysine-Aspirin Bronchoprovocation Test in ASA-Sensitive Asthmatic Patients
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Kim SS, Park HS, Yoon HJ, Lee YM, Lee SK, Nahm DH
- KMID: 1099791
- J Korean Med Sci.
- 2003 Feb;18(1):42-47.
- doi: 10.3346/jkms.2003.18.1.42
To investigate the pathogenic mechanism of late asthmatic response in comparison to early asthmatic response, changes of serum neutrophil chemotactic activity (NCA) using the Boyden chamber method and histamine level... -
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