- Combined effects of soy isoflavone and lecithin on bone loss in ovariectomized mice
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Kim SB, Assefa F, Lee SJ, Park EK, Kim SS
- KMID: 2520657
- Nutr Res Pract.
- 2021 Oct;15(5):541-554.
- doi: 10.4162/nrp.2021.15.5.541
BACKGROUND/OBJECTIVES: Isoflavones (ISFs) are effective in preventing bone loss, but not effective enough to prevent osteoporosis. Mixtures of soy ISF and lecithin (LCT) were prepared and characterized in an attempt... -
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- The Neuropeptide Spexin Promotes the Osteoblast Differentiation of MC3T3-E1 Cells via the MEK/ERK Pathway and Bone Regeneration in a Mouse Calvarial Defect Model
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Assefa F, Kim JA, Lim J, Nam SH, Shin HI, Park EK
- KMID: 2525417
- Tissue Eng Regen Med.
- 2022 Feb;19(1):189-202.
- doi: 10.1007/s13770-021-00408-2
BACKGROUND: The neural regulation of bone regeneration has emerged recently. Spexin (SPX) is a novel neuropeptide and regulates multiple biological functions. However, the effects of SPX on osteogenic differentiation need... -
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- Secretoneurin, a Neuropeptide, Enhances Bone Regeneration in a Mouse Calvarial Bone Defect Model
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Assefa F, Lim J, Kim JA, Ihn HJ, Lim S, Nam SH, Bae YC, Park EK
- KMID: 2514876
- Tissue Eng Regen Med.
- 2021 Apr;18(2):315-324.
- doi: 10.1007/s13770-020-00304-1
BACKGROUND: This study investigates the effects of a neuropeptide, secretoneurin (SN), on bone regeneration in an experimental mouse model. METHODS: The effects of SN on cell proliferation, osteoblast marker genes expression,... -
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