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Experimental Atherosclerosis in Pigs

Lee KT

No abstract available.
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Chronological effects of atherogenic diets on the aorta, liver and spleen of rabbits

Song SH, Min BI, Lee JH, Cho KS

To investigate the temporal progression of atherogenesis on the aorta and involvement of the monocyte-macrophage system in the liver and spleen, we fed 74 rabbits with high fat (14 or...
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Expression of leptin receptor (Ob-R) in human atherosclerotic lesions: potential role in intimal neovascularization

Kang SM, Kwon HM, Hong BK, Kim D, Kim IJ, Choi EY, Jang Y, Kim HS, Kim MS, Kwon HC

Neovascularization of the adventitial vasa vasorum with extension into the intima of atherosclerotic lesions is frequently observed, but its pathophysiological significance is still subject to debate. Recently, leptin, the product...
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Effect of angiopeptin and aspirin on accelerated graft atherosclerosis in transplanted mouse heart

Lee JR, Yang JH, Kim EK, Seo JW

In this study of the inhibitory effects of angiopeptin and aspirin on the development of accelerated graft atherosclerosis (AGAS), 22 B10.BR mice received intra-abdominal heterotopic heart transplants from B10.A mice,...
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Expression of osteopontin in calcified coronary atherosclerotic plaques

Kwon HM, Hong BK, Kang TS, Kwon K, Kim HK, Jang Y, Choi D, Park HY, Kang SM, Cho SY, Kim HS

Advanced atherosclerosis is often associated with dystrophic calcification and remodeling of extracellular matrix of vascular wall. Recently many studies have documented a general relationship between calcification and severity of coronary...
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Surface Expression of P-selectin on Platelets Is Related with Clinical Worsening in Acute Ischemic Stroke

Cha JK, Jeong MH, Kim EK, Lim YJ, Ha BR, Kim SH, Kim JW

Platelet activation has a critical role in arterial disorders. In this study, we showed that the upregulation of P-selectin expression on platelets was related with clinical worsening in acute...
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Serologic and histopathologic study of Chlamydia pneumoniae infection in atherosclerosis: a possible pathogenetic mechanism of atherosclerosis induced by Chlamydia pneumoniae

Song YG, Kwon HM, Kim JM, Hong BK, Kim DS, Huh AJ, Chang KH, Kim HY, Kang TS, Lee BK, Choi DH, Jang YS, Kim HS

Chronic infection and inflammation have recently been implicated as important etiologic agents for atherosclerosis in general and, in particular, ischemic heart disease. Several agents have been suggested as possible candidates...
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Surface features of human aortic atherosclerosis as seen with scanning electron microscopy

Song SH, Roach MR

Using SEM, we have observed surface structures of atherosclerotic lesions of human aortas obtained from autopsies ranging from 59 to 84 years of age (5 males and 4 females). We...
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Coexpression of cyclooxygenase-2 and matrix metalloproteinases in human aortic atherosclerotic lesions

Hong BK, Kwon HM, Lee BK, Kim D, Kim IJ, Kang SM, Jang Y, Cho SH, Kim HK, Jang BC, Cho SY, Kim HS, Kim MS, Kwon HC, Lee N

Inflammation appears to have a major role in the development of atherosclerosis. Cyclooxygenase-2 (COX-2) is involved in the inflammatory response via the generation of prostanoids that, in turn, are involved...
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Acute Geometric Changes of the Mitral Annulus after Coronary Occlusion: A Real-Time 3D Echocardiographic Study

Kwan J, Yeom BW, Jones M, Qin JX, Zetts AD, Thomas JD, Shiota T

We performed real-time 3D echocardiography in sixteen sheep to compare acute geometric changes in the mitral annulus after left anterior descending coronary artery (LAD, n=8) ligation and those after left...
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Prevalence of foam cells and helper-T cells in atherosclerotic plaques of Korean patients with carotid atheroma

Lee WH, Ko YH, Kim DI, Lee BB, Park JE

  • KMID: 759503
  • Korean J Intern Med.
  • 2000 Jul;15(2):117-121.
BACKGROUND: Inflammation and activation of immune cells have important roles in the pathogenesis of atherosclerosis. We analyzed the involvement of various immune...
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The Impact of the Preoperative Severity of Target-Vessel Stenosis on the Short-Term Patency of Radial Artery Grafts

Joung B, Park S, Choi D, Choi BW, Ko YG, Yoo KJ, Jang Y, Chung NS, Cho SY

The fate of a grafted radial artery remains unknown. The purpose of this study was to determine whether the preoperative severity of stenosis of the target vessel influence short-term patency...
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