- Antiviral Effect of Entecavir Switching Therapy in Chronic Hepatitis B Patients with Clevudine-associated Myopathy
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Tak WY
- KMID: 1775779
- Korean J Gastroenterol.
- 2013 Jan;61(1):1-2.
- doi: 10.4166/kjg.2013.61.1.1
No abstract available. -
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- Clevudine induced diabetes mellitus in a patient with chronic hepatitis B
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Kim GW, Lee MY, Kim SY, Kim JH, Lee JH, Chung CH
- KMID: 1458437
- Korean J Med.
- 2010 Nov;79(5):569-572.
Several studies have documented that various agents can induce diabetes mellitus, such as steroids, thiazides, anti-psychotic agents, and anti-viral agents. Many antiviral agents are also reported to impair insulin resistance... -
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- Clevudine therapy in patients with chronic hepatitis B
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Lee KS
- KMID: 1381432
- Korean J Hepatol.
- 2009 Jun;15(2):119-121.
- doi: 10.3350/kjhep.2009.15.2.119
No abstract available. -
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- Myopathy due to Chronic Clevudine Therapy: A Case Report
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Kim JY, Yoon YS, Park KD, Koo H
- KMID: 1472646
- Korean J Pathol.
- 2009 Dec;43(6):575-579.
- doi: 10.4132/KoreanJPathol.2009.43.6.575
A 40-year-old man with chronic hepatitis B complained of progressive weakness of the proximal muscles and edema of both legs. He had been receiving long-term clevudine (nucleoside analogue reverse transcriptase... -
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- Clinical and Virological Responses to Clevudine Therapy of Hepatocelluar Carcinoma Patients with Chronic Hepatitis B
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Woo SM, Park JW, Lee WJ, Kim CM
- KMID: 2167280
- Gut Liver.
- 2011 Mar;5(1):82-87.
BACKGROUND/AIMS: The clinical effects of clevudine have been reported in patients with chronic hepatitis B virus infections (CHIs). In this investigation, we assessed whether clevudine induced biochemical and virological improvements... -
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- A YIDD Mutation in a Case of Recurrent Hepatitis B after Liver Transplantation Induced by an S-escape Mutant
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Oh YJ, Park YM, Hong SP, Shin SK, Ji SI, Kim BH, Park SJ, Hong Z
- KMID: 2284195
- Gut Liver.
- 2010 Jun;4(2):253-257.
A 47-year-old woman underwent orthotopic liver transplantation (OLT) for hepatitis B virus (HBV)-related end-stage liver cirrhosis. The patient received hepatitis B immunoglobulin prophylaxis after OLT. Despite the protective level of... -
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- Antiviral Therapy for Chronic Hepatitis B
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Lee KS
- KMID: 2188062
- J Korean Med Assoc.
- 2009 Aug;52(8):831-837.
- doi: 10.5124/jkma.2009.52.8.831
Chronic hepatitis B infection is the most common cause of chronic liver diseases in Korea and can induce chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. If patients have significant viral... -
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- Experience of Anti-Viral Therapy in Hepatitis B-Associated Membranous Nephropathy, Including Lamivudine-Resistant Strains
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Sun IO, Hong YA, Park HS, Choi SR, Chung BH, Park CW, Yang CW, Kim YS, Choi BS
- KMID: 2432933
- Korean J Intern Med.
- 2012 Dec;27(4):411-416.
BACKGROUND/AIMS: Chronic hepatitis B infection is a common cause of secondary membranous nephropathy (MN) in endemic areas. Lamivudine treatment improves renal outcome in patients with hepatitis B virus-associated MN (HBV-MN),... -
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- Comparison of entecavir and clevudine for treatment of chronic hepatitis B
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Kim DH, Kim SH, Kim JH, Park BK, Suh JH, Cho YS, Choi JW, Lee CK
- KMID: 2259138
- Korean J Med.
- 2010 May;78(5):595-601.
BACKGROUND/AIMS: Entecavir (ETV) and clevudine (CLV) are potent inhibitors of hepatitis B virus (HBV) DNA polymerase and have demonstrated clinical efficacy. No comparative study has reported on these two medications... -
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- Long-Term Treatment Efficacy and Safety of Clevudine Therapy in Naive Patients with Chronic Hepatitis B
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Choung BS, Kim IH, Jeon BJ, Lee S, Kim SH, Kim SW, Lee SO, Lee ST, Kim DG
- KMID: 2167421
- Gut Liver.
- 2012 Oct;6(4):486-492.
BACKGROUND/AIMS: Clevudine (CLV) has potent antiviral activity against chronic hepatitis B (CHB) virus infection. The long-term efficacy and safety of CLV therapy in naive patients with CHB were investigated. METHODS: In... -
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- Treatment Outcomes of Clevudine versus Lamivudine at Week 48 in Naive Patients with HBeAg Positive Chronic Hepatitis B
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Kim IH, Lee S, Kim SH, Kim SW, Lee SO, Lee ST, Kim DG, Choi CS, Kim HC
- KMID: 1713959
- J Korean Med Sci.
- 2010 May;25(5):738-745.
- doi: 10.3346/jkms.2010.25.5.738
The authors assessed the efficacy and antiviral resistance of 48-week clevudine therapy versus lamivudine in treatment of naive patients with HBeAg positive chronic hepatitis B. In this retrospective study, a... -
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- Efficacy of Entecavir Switching Therapy in Chronic Hepatitis B Patients with Clevudine-induced Myopathy
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Lee JW, Lee YJ, Lee JJ, Kim JH, Jung YK, Kwon OS, Choi DJ, Kim YS, Kim JH
- KMID: 1775784
- Korean J Gastroenterol.
- 2013 Jan;61(1):30-36.
- doi: 10.4166/kjg.2013.61.1.30
BACKGROUND/AIMS: Clevudine is a potent antiviral agent against HBV. However, long-term clevudine therapy may cause myopathy. This study was carried out to identify the efficacy of entecavir switching therapy in... -
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- Clinical and Pathological Features of Clevudine Induced Myopathy
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Seok JI, Kim DS, Park MS, Nam TS, Song HS, Park YE, Kim SY, Kim YS, Huh SY, Lee DK, Jo HY, Lee CH
- KMID: 2343449
- J Korean Neurol Assoc.
- 2013 Feb;31(1):26-31.
BACKGROUND: Clevudine (Revovir(R)) is a recently introduced antiviral drug, and clinical trials have demonstrated its potent, sustained antiviral activity without specific adverse events. However, several studies have found severe myopathy... -
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- Small Animal PET Imaging with [124I]FIAU for Herpes Simplex Virus Type 1 Thymidine Kinase Gene Expression in a Hepatoma Model
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Chae MJ, Lee TS, Kim JY, Woo GS, Jumg WS, Chun KS, Kim JH, Lee JS, Ryu JS, Cheon GJ, Choi CW, Lim SM
- KMID: 2313046
- Nucl Med Mol Imaging.
- 2008 Jun;42(3):235-234.
PURPOSE: The HSV1-tk gene has been extensively studied as a type of reporter gene. In hepatocellular carcinoma (HCC), only a small proportion of patients are eligible for surgical resection and... -
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- Management of Clevudine-Resistant Chronic Hepatitis B: A Multicenter Cohort Study
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Cho EY, Yim HJ, Jung YK, Suh SJ, Seo YS, Kim JH, Kim HS, Lee SH, Ahn SH, Lee JI, Jeong SH, Kim JW, Lee JW, Kim IH, Kim HS, Park SJ, Lee JM, Hwang SG
- KMID: 2412164
- Gut Liver.
- 2017 Jan;11(1):129-135.
- doi: 10.5009/gnl15597
BACKGROUND/AIMS: Data are lacking regarding the management of chronic hepatitis B (CHB) with resistance to clevudine (CLV). This study evaluated the efficacy of different rescue therapies for CLV-resistant CHB. METHODS: Patients... -
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- Development of Clevudine Resistance after Switching from Lamivudine in a Patient with Chronic Hepatitis B
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Koh KH, Kang CJ, Kim DH, Choi YW, Kim MJ, Cheong JY, Cho SW
- KMID: 783106
- Korean J Gastroenterol.
- 2008 Nov;52(5):325-328.
Clevudine is a nucleoside analog of the unnatural beta-L configuration which has potent antiviral activity against hepatitis B virus (HBV). Clevudine is expected to have similar pattern of resistance profile... -
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- Management of Chronic Hepatitis B in Treatment-Naive Patients
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Cheong JY
- KMID: 1767538
- Korean J Gastroenterol.
- 2008 Jun;51(6):338-345.
Chronic hepatitis B (CHB) is a serious health problem in Korea. The natural history of chronic HBV infection has been divided into 4 phases: immune tolerance, immune clearance, inactive HBsAg... -
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- Management of Antiviral-Resistant Chronic Hepatitis B Virus Infection
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Yim HJ
- KMID: 1767539
- Korean J Gastroenterol.
- 2008 Jun;51(6):346-359.
Substantial progress has been made in the treatment of chronic hepatitis B during the past decade. Nucleos(t)ide analogues are now widely used due to their convenience, less side effects, and... -
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- Forty-eight weeks treatment with clevudine 30 mg qd versus lamivudine 100 mg qd for chronic hepatitis B infection: a double-blind randomized study
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Lau GK, Leung N
- KMID: 1717327
- Korean J Hepatol.
- 2010 Sep;16(3):315-320.
- doi: 10.3350/kjhep.2010.16.3.315
BACKGROUND/AIMS: Clevudine is a pyrimidine analogue with potent activity against hepatitis B virus (HBV) replication in vitro. In a previous pivotal phase III clinical study, 24 weeks treatment with clevudine... -
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- Efficacy of Initial Treatment with Clevudine in Naive Patients with Chronic Hepatitis B
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Yang HW, Lee BS, Lee TH, Lee HY, Nam KW, Kang YW, Chae HB, Kim SH, Kim SB, Lee HI, Kim AN, Song IH, Lee SH, Kim HS
- KMID: 964717
- Korean J Intern Med.
- 2010 Dec;25(4):372-376.
- doi: 10.3904/kjim.2010.25.4.372
BACKGROUND/AIMS: Clevudine, a pyrimidine nucleoside analogue, has potent antiviral effects in patients with chronic viral hepatitis B (CHB). We report the efficacy of initial treatment with clevudine in naive patients... -
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