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Intracerebral Hemorrhage related to Phentermine as an Appetite Suppressant

Lee WJ, Kang MK, Shin HR, Kim TJ, An SJ, Mo H, Nam K, Yoon BW

We present a case report indicating that the administration of phentermine, an appetite suppressant with sympathomimetic activity, can provoke an intracerebral hemorrhage. A 48-year-old woman with no previously established cerebrovascular...
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A Case of Ischemic Stroke Associated with Phendimetrazine as an Appetite Suppressant

Park JK, Hong KS, Cho YJ, Jeong SW, Oh EJ, Park SY, Lee DH, Cho JY

  • KMID: 2065607
  • J Korean Neurol Assoc.
  • 2006 Oct;24(5):465-467.
The published case series have suggested that appetite suppressants had some association with the development of stroke. Phendimetrazine is an appetite suppressant with sympathomimetic activity and it has a similar...
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Psychotic Disorder Induced by Appetite Suppressants, Phentermine or Phendimetrazine: A Case Series Study

Kwak S, Youn T, Lee NY, Chung IW, Kim SH

OBJECTIVES: A retrospective case series study was conducted to investigate the clinical characteristics of psychotic disorders induced by appetite suppressants, phentermine and phendimetrazine. METHODS: A retrospective electronic medical record review identified...
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A Case of Phendimetrazine Induced-Psychotic Disorder and Dependence

Yun JA, Park WR, Yu JC, Choi KS

  • KMID: 2343635
  • J Korean Neuropsychiatr Assoc.
  • 2013 Sep;52(5):402-405.
Phendimetrazine and related amphetamine-like compounds are used widely as appetite suppressants in Korea. We report on a patient who developed psychotic disorder and dependence while using phendimetrazine. A 25-year-old female...
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Gene Expression Profiling in C57BL/6 Mice Treated with the Anorectic Drugs Sibutramine and Phendimetrazine and Their Mechanistic Implications

Ko MJ, Choi HS, Ahn JI, Kim SY, Jeong HS, Chung HJ

  • KMID: 2166406
  • Genomics Inform.
  • 2008 Sep;6(3):117-125.
Recently, obesity has become a worldwide public health concern and the use of anorectic drugs has drastically increased. In this study, sibutramine and phendimetrazine, representative marketed anorectics, were repeatedly administered...
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Effect of Weight Reduction on Obesity-specific Quality of Life (QOL) in Obese Subjects

Lee JS, Shin CI, Kim BT, Lee KW, Park HS

  • KMID: 2270768
  • Korean J Obes.
  • 2006 Jun;15(2):106-113.
BACKGROUND: It has been reported that the quality of life of obese patients is reduced. In this regard, this study attempts to investigate if there are any changes in the...
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Studies on the Association between Phenylpropanolamine (PPA) and Hemorrhagic Stroke in Other Countries

Lee SM, Yoon BW, Park BJ

  • KMID: 2303914
  • Korean J Epidemiol.
  • 2004 Dec;26(2):1-7.
OBJECTIVES: Phenylpropanolamine (PPA) had been used widely as cold remedies or appetite suppressants. However, products containing PPA were withdrawn in sequence in the US, Japan, and Korea due to the...
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Effects of anti-obesity drugs, phentermine and mahuang, on the behavioral patterns in Sprague-Dawley rat model

Go RE, Hwang KA, Kim SH, Lee MY, Kim CW, Jeon SY, Kim YB, Choi KC

According to WHO global estimates from 2008, more than 1.4 billion adults were overweight and among them, over 200 million men and 300 million women were obese. Although the main...
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Effects on Weight Reduction and Safety of Short-Term Phentermine Administration in Korean Obese People

Kim KK, Cho HJ, Kang HC, Youn BB, Lee KR

The phentermine, an appetite suppressant, has been widely applied in Korea since 2004. However, there have been relatively few reports about the efficacy and the safety of phentermine in Korea....
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Changes of Body Weight and Inflammatory Markers after 12-Week Intervention Trial: Results of a Double-Blind, Placebo-Control Pilot Study

Joo NS, Kim SM, Kim KM, Kim CW, Kim BT, Lee DJ

PURPOSE: Low grade inflammation is a well-known characteristic in obese subjects. We investigated body weight changes and inflammatory markers after 12-week intervention trial. MATERIALS AND METHODS: Twenty-six obese subjects were enrolled...
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