- Effects of mastoparan on a vascular contractility in rabbit aorta
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Lee YH, Kang SI, Ahn DS, Lee HY, Choi EJ, Kang BS
- KMID: 1123181
- Yonsei Med J.
- 1995 Jun;36(3):262-270.
- doi: 10.3349/ymj.1995.36.3.262
Mastoparan is an amphiphilic tetradecapeptide derived from wasp venom which activates G-proteins. Several secondary effects have been attributed to this peptide, including activation of phospholipase and phosphatidylinositol kinase. The aim... -
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- Effects of adenosine tetraphosphate (ATPP) on vascular tone in the isolated rat aorta
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Lee JW, Kong ID, Park KS, Jeong SW
- KMID: 699860
- Yonsei Med J.
- 1995 Dec;36(6):487-496.
- doi: 10.3349/ymj.1995.36.6.487
Effects of a platelet-released, naturally occurring nucleotide, adenosine 5'-tetraphosphate (ATPP) on vascular tone were analyzed in the isolated rat aorta. Under resting tension ATPP (1 approximately 100 microM) elicited concentration-dependent... -
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- Inhibitory Effect of Fentanyl on Phenylephrine-Induced Contraction of the Rat Aorta
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Park KE, Sohn JT, Jeong YS, Sung HJ, Shin IW, Lee HK, Chung YK
- KMID: 1758571
- Yonsei Med J.
- 2009 Jun;50(3):414-421.
- doi: 10.3349/ymj.2009.50.3.414
PURPOSE: Fentanyl was reported to inhibit the alpha1-adrenoceptor agonist-induced contraction. The goal of this in vitro study was to identify the alpha1-adrenoceptor subtype primarily involved in the fentanyl-induced attenuation of... -
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- Do Acute Changes in Heart Rate by Isoproterenol Affect Aortic Stiffness in Patients with Hypertension?
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Rhee MY, Kwon NY, Kim JD, Song SH, Yoon YW, Lee MY, Kim YK
- KMID: 759682
- Korean J Intern Med.
- 2004 Mar;19(1):33-37.
BACKGROUND: Increased aortic stiffness is a independent risk factor of cardiovascular disease in patients with hypertension. Acute changes of the heart rate (HR) have been reported not to affect the... -
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- Syringaresinol causes vasorelaxation by elevating nitric oxide production through the phosphorylation and dimerization of endothelial nitric oxide synthase
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Chung BH, Kim S, Kim JD, Lee JJ, Baek YY, Jeoung D, Lee H, Choe J, Ha KS, Won MH, Kwon YG, Kim YM
- KMID: 1245262
- Exp Mol Med.
- 2012 Mar;44(3):191-201.
- doi: 10.3858/emm.2012.44.3.014
Nitric oxide (NO) produced by endothelial NO synthase (eNOS) plays an important role in vascular functions, including vasorelaxation. We here investigated the pharmacological effect of the natural product syringaresinol on... -
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- Efficacy of Irbesartan on Left Ventricular Mass and Arterial Stiffness in Hypertensive Patients
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Park CG, Ahn JC, Hong SJ, Kim EJ, Lee SJ, Park SM, Seo HS, Oh DJ
- KMID: 1785606
- Korean J Intern Med.
- 2006 Jun;21(2):103-108.
- doi: 10.3904/kjim.2006.21.2.103
BACKGROUND: Increased aortic stiffness measured by pulse wave velocity (PWV) and left ventricular hypertrophy (LVH) are independent risk factors of cardiovascular events in hypertensive patients. We have conducted a... -
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