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Changes of Cytoskeletal System in Neurodegenerative Disease: Immunohistochemical Characterization of Neurofibrillary Changes Induced by Mitotic Spindle Inhibitors

Koo H

In experimental neurogenerative diseases, aluminum(Al) intoxication and axotomized sensory neurons showed an abnormal accumulation of neurofilaments(NF) in the neuronal perikarya. These NF contain phosphorylated(ph) epitopes that are not detectable in...
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A Case of Therapy-related Acute Myeloid Leukemia associated with inv(16)

Lee SY, Kim M, Lim J, Kim Y, Han K, Kim SY, Kim HJ, Park IY

The inv(16)(p13q22) is found in de novo AML and is closely associated with the FAB subtype M4eo. The inv(16) is rarely reported in therapy-related AML (t-AML) patients. Herein, we report...
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The Effect of Antimetabolites for Inhibiting the Proliferation of Rabbit Lens Epithelial Cells in Vitro

Lim SJ, Ahn DH, You YS, Kim HB

  • KMID: 2336742
  • J Korean Ophthalmol Soc.
  • 1999 Jan;40(1):94-103.
The most common cause of blurred vision after extracapsular cataract extraction is known to be an opacification of the posterior lens capsule. The pathogenesis of posterior lens capsule opacification is...
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Arsenic trioxide induces depolymerization of microtubules in an acute promyelocytic leukemia cell line

Baek JH, Moon CH, Cha SJ, Lee HS, Noh EK, Kim H, Won JH, Min YJ

BACKGROUND: Arsenic trioxide (As2O3) is a well-known and effective treatment that can result in clinical remission for patients diagnosed with acute promyelocytic leukemia (APL). The biologic efficacy of As2O3 in...
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