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Genetic Polymorphisms in VIR Genes among Indian Plasmodium vivax Populations

Gupta P, Pande V, Das A, Singh V

The vir genes are antigenic genes and are considered to be possible vaccine targets. Since India is highly endemic to Plasmodium vivax, we sequenced 5 different vir genes and investigated...
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Evolution of Genetic Polymorphisms of Plasmodium falciparum Merozoite Surface Protein (PfMSP) in Thailand

Kuesap J, Chaijaroenkul W, Ketprathum K, Tattiyapong P, Na-Bangchang K

Plasmodium falciparum malaria is a major public health problem in Thailand due to the emergence of multidrug resistance. The understanding of genetic diversity of malaria parasites is essential for developing...
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Allelic Diversity and Geographical Distribution of the Gene Encoding Plasmodium falciparum Merozoite Surface Protein-3 in Thailand

Sawaswong , Simpalipan P, Siripoon N, Harnyuttanakorn P, Pattaradilokrat S

Merozoite surface proteins (MSPs) of malaria parasites play critical roles during the erythrocyte invasion and so are potential candidates for malaria vaccine development. However, because MSPs are often under strong...
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Evaluation of alpha-Tubulin as an Antigenic and Molecular Probe to Detect Giardia lamblia

Kim J, Shin MH, Song KJ, Park SJ

The alpha/beta-tubulin heterodimer is the basic subunit of microtubules in eukaryotes. Polyclonal antibodies specific to recombinant alpha-tubulin of Giardia lamblia were made, and found effective as a probe to specifically...
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Genetic characteristics of the Korean isolate KI-1 of Toxoplasma gondii

Lin A, Shin EH, Kim TY, Park JH, Guk SM, Chai JY

Toxoplasma gondii tachyzoites were isolated from an ocular patient in the Republic of Korea and maintained in the laboratory (designated KI-1). In the present study, its genotype was determined by...
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Antigenic diversity of Theileria major piroplasm surface protein gene in Jeju black cattle

Ko MS, Lee KK, Hwang KK, Kim BS, Choi GC, Yun YM

Piroplasms are tick-transmitted, intracellular, hemoprotozoan parasites that cause anorexia, fever, anemia, and icterus. Theileriosis is caused by Theileria sergenti and causes major economic losses in grazing cattle in Japan and Korea....
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Genetic diversity in merozoite surface protein (MSP)-1 and MSP-2 genes of Plasmodium falciparum in a major endemic region of Iran

Heidari A, Keshavarz , Rokni MB, Jelinek T

Merozoite surface protein-1 (MSP-1) and merozoite surface protein-2 (MSP-2) were used to develop vaccines and to investigate the genetic diversity in Plasmodium falciparum malaria in Iran. Nested polymerase chain reaction...
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