- JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells
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Choi DW, Kim DK, Kanai Y, Wempe MF, Endou H, Kim JK
- KMID: 2395254
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):599-607.
- doi: 10.4196/kjpp.2017.21.6.599
Most normal cells express L-type amino acid transporter 2 (LAT2). However, L-type amino acid transporter 1 (LAT1) is highly expressed in many tumor cells and presumed to support their increased... -
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