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A clinicopathologic study on the diffuse malignant lymphoma: a morphologic and immunophenotypic analysis in 62 patients at Harbor-UCLA Medical Center

Lee JH, Sun NC, Salahi W, Chen H, Yang MH

In order to compare the prognoses of patients with diffuse malignant lymphomas on the basis of histology and immunophenotypes, we retrospectively studied 62 cases of diffuse lymphoma arising in...
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Langerhans Cell Sarcoma Arising from Langerhans Cell Histiocytosis: A Case Report

Lee JS, Ko GH, Kim HC, Jang IS, Jeon KN, Lee JH

Langerhans cell sarcoma (LCS) is a neoplastic proliferation of Langerhans cells that have overtly malignant cytologic features. It is a very rare disease and theoretically, it can present de novo...
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CD137 induces adhesion and cytokine production in human monocytic THP-1 cells

Choi JW, Lee HW, Roh GS, Kim HH, Kwack KB

  • KMID: 755745
  • Exp Mol Med.
  • 2005 Apr;37(2):78-85.
CD137, which is expressed on activated T cells, plays a critical role in inflammatory responses. However, the exact role that CD137 plays in monocytes is not fully known. Here we...
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Expression of dendritic cell markers on cultured neutrophils and its modulation by anti-apoptotic and pro-apoptotic compounds

Park HY, Jin JO, Song MG, Park JI, Kwak JY

  • KMID: 756066
  • Exp Mol Med.
  • 2007 Aug;39(4):439-449.
Neutrophils are also known to acquire the characteristics of dendritic cells (DCs) under the appropriate conditions. In this study, neutrophils were cultivated in vitro in the presence or absence of...
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A decrease in the expression of CD63 tetraspanin protein elevates invasive potential of human melanoma cells

Jang HI, Lee H

  • KMID: 1109322
  • Exp Mol Med.
  • 2003 Aug;35(4):317-323.
CD63, which belongs to the tetraspanin membrane proteins, has been proposed to play an important role in inhibiting melanoma metastasis. To determine whether reduction of CD63 expression, which frequently occurs...
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Multi-drug resistance (MDR1) gene expression in de novo acute leukemia cells: correlations with CD surface markers and treatment outcome

Jiang EZ, Chang YJ, Lee JW, Lee WK, Kim JS, Sohn SK, Lee KB, Suh JS

One important mechanism of drug resistance in acute leukemia is the overexpression of the multi-drug resistance (MDR1) gene that encodes a 170-kDa membrane protein called P-glycoprotein. To estimate the...
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Sequential evolution of IL-17 responses in the early period of allograft rejection

Min SI, Ha J, Park CG, Won JK, Park YJ, Min SK, Kim SJ

In addition to CD4+CD25+Foxp3+ regulatory T (T(reg)) cells which protect against autoimmune tissue injury, IL-17-producing CD4+ T (Th17) cells have been recently described and shown to play a crucial role...
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