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Autophagy in Innate Recognition of Pathogens and Adaptive Immunity

Oh JE, Lee HK

Autophagy is a specialized cellular pathway involved in maintaining homeostasis by degrading long-lived cellular proteins and organelles. Recent studies have demonstrated that autophagy is utilized by immune systems to protect...
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Activated natural killer cell-mediated immunity is required for the inhibition of tumor metastasis by dendritic cell vaccination

Kim A, Noh YW, Kim KD, Jang YS, Choe YK, Lim JS

  • KMID: 1123764
  • Exp Mol Med.
  • 2004 Oct;36(5):428-443.
Immunization with dendritic cells (DCs) pulsed with tumor antigen can activate tumor-specific cytotoxic T lymphocytes (CTL), which is responsible for tumor protection and regression. In this study, we examined whether...
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