- A Case Report of a Poor Metabolizer of CYP2D6 Presented with Unusual Responses to Nortriptyline Medication
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Lee SY, Ki CS, Hong KS, Kim JW
- KMID: 1733521
- J Korean Med Sci.
- 2004 Oct;19(5):750-752.
- doi: 10.3346/jkms.2004.19.5.750
We present a case with decreased metabolic activity of CYP2D6, a cytochrome P450 enzyme catalyzing the metabolism of nortriptyline (NT). Conventional dosage regimen led to toxic plasma concentration of NT... -
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