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A Case Report of a Patient Carrying CYP2C9*3/4 Genotype with Extremely Low Warfarin Dose Requirement

Lee SY, Nam MH, Kim JS, Kim JW

We report a case of intolerance to warfarin dosing due to impaired drug metabolism in a patient with CYP2C9*3/*4. A 73-yr-old woman with atrial fibrilation was taking warfarin. She attained...
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Efficacy of Femoral Vascular Closure Devices in Patients Treated with Anticoagulant, Abciximab or Thrombolytics during Percutaneous Endovascular Procedures

Kim HY, Choo SW, Roh HG, Han H, Kim SS, Lee JY, Park YR, Lee SH, Shin SW, Park KB, Do YS, Cho SK, Lee IH, Kim SM, Byun HS, Jeon P

OBJECTIVE: This study assessed the outcomes of using vascular closure devices following percutaneous transfemoral endovascular procedures in the patients who were treated with heparin, abciximab or thrombolytics (urokinase or t-PA)...
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Heparin attenuated neutrophil infiltration but did not affect renal injury induced by ischemia reperfusion

Shin CS, Han JU, Kim JL, Schenarts , Traber LD, Hawkins H, Traber DL

Although heparin is better known as an anticoagulant, it also has several anti-inflammatory effects. Heparin is known to inhibit neutrophil adhesion, chemotaxis and oxygen free radical production. In...
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