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Antibodies to human T-cell lymphotropic virus type I (HTLV-I) by particle agglutination (PA) test in Korean blood donors

Kim JM, Song YG, Oho YC, Park HC, Kwon KH, Kim E, Lee SH, Kim KH

HTLV-I infection is a recently recognized disease entity that is common in some tropical and subtropical areas, including the southwestern district of Japan. Despite the geographical proximity and frequent...
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Anticardiolipin and anti-beta2-glycoprotein I antibodies in Behcet's disease

Kang HJ, Lee YW, Han SH, Cho HC, Lee KM

To investigate prevalence of anticardiolipin antibodies (aCL) in patients with Behcet's disease (BD) and to determine whether they are related to anti-beta2-glycoprotein I antibodies (aGPI), we measured aCL and...
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Behcet's disease sera containing antiendothelial cell antibodies promote adhesion of T lymphocytes to cultured human dermal microvascular endothelial cells

Lee KH, Chung HS, Bang D, Lee S

Antiendothelial cell antibodies (AECA) have been detected in the sera of patients of autoimmune diseases showing vasculitis. Using IgM-ELISA, we found AECA in 42 (56%) of 75 sera...
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In vivo hepatitis B virus-neutralizing activity of an anti-HBsAg humanized antibody in chimpanzees

Kim SH, Oh HK, Ryu CJ, Park SY, Hong HJ

Previously, we constructed a humanized antibody (HuS10) that binds to the common a antigenic determinant on the S protein of HBV. In this study, we evaluated its HBV-neutralizing activity in...
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Investigation of Serum Angiotensin II Type 1 Receptor Antibodies at the Time of Renal Allograft Rejection

Lee H, Kim JI, Moon IS, Chung BH, Yang CW, Kim Y, Han K, Oh EJ

BACKGROUND: Angiotensin II type 1 receptor (AT1R) is responsible for cardiovascular effects mediated by angiotensin II. This study aimed to investigate the impact of antibodies directed against AT1R (anti-AT1R) in...
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Definition, Diagnosis, and Prevalence of Occult Hepatitis B Virus Infection

Kim YS

Occult HBV infection is characterized by the absence of serum HBsAg with persistence of low level of intrahepatic HBV DNA. Several suggested mechanisms for the origin of occult HBV infection...
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Inactive hepatitis B surface antigen carriers and intrafamilial tramsmission: results of a 10-year study

Demirturk , Demirdal T

BACKGROUND/AIMS: The aims of the present study were to determine the outcomes of inactive hepatitis B virus (HBV) surface antigen (HBsAg) carriers over a 10-year study period and to elucidate...
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Factors associated with positive predictability of the anti-HCV ELISA method with confirmatory RT-PCR

Kim YS, Lee HS, Ahn YO

The positive predictability of anti-HCV ELISA is low, especially, in blood donors and in healthy populations. False positive anti-HCV results pose some difficulties in medical practice and in blood screening....
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Risk of Pancreatic Cancer in Relation to ABO Blood Group and Hepatitis C Virus Infection in Korea: A Case-Control Study

Woo SM, Joo J, Lee WJ, Park SJ, Han SS, Kim TH, Koh YH, Kim HB, Hong EK

Several studies have reported that ABO blood group, hepatitis B virus (HBV) and hepatitis C virus (HCV) infection contribute to the development of pancreatic cancer. The aim of this study...
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Prevalence of Occult Hepatitis B Virus Infection in Hemodialysis Patients

Yoo JH, Hwang SG, Yang DH, Son MS, Kwon CI, Ko KH, Hong SP, Park PW, Rim KS

BACKGROUND/AIMS: The prevalence of occult HBV infection depends on the prevalence of HBV infection in the general population. Hemodialysis patients are at increased risk for HBV infection. The aim of...
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Evaluation of Two Automated Instruments for Pre-transfusion Testing: AutoVue Innova and Techno TwinStation

Shin SY, Kwon KC, Koo SH, Park JW, Ko CS, Song JH, Sung JY

BACKGROUND: Despite the advances in total laboratory automation, a considerable amount of work in blood banks is still done using outdated manual methods. Some automated pre-transfusion testing instruments have recently...
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Monitoring antibody titers to recombinant Core-NS3 fusion polypeptide is useful for evaluating hepatitis C virus infection and responses to interferon-alpha therapy

Park YM, Byun BH, Choi JY, Bae SH, Kim BS, So HS, Ryu WS

To evaluate the clinical feasibility of the antibody titer against a chimeric polypeptide (named Core 518), in which a domain of Core and NS3 of hepatitis C virus (HCV) was...
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A study of hepatitis B virus reactivation associated with rituximab therapy in real-world clinical practice: a single-center experience

Oh MJ, Lee HJ

BACKGROUND/AIMS: The widespread use of cytotoxic chemotherapy and immunosuppressants has resulted in reactivation of hepatitis B virus (HBV) recently becoming an issue. Although rituximab (an anti-CD20 monoclonal antibody) has revolutionized...
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A Study on Viral Hepatitis Markers and Abnormal Liver Function Test in Adults Living in Northwest Area of Chungnam

Kim SB, Lee WK, Choi H, Kim SM, Noh R, Kang HY, Lee SS, Ra SS, Gong JH, Shin HD

BACKGROUND/AIMS: We studied the prevalence of chronic hepatitis B, C and abnormality on liver function among the population in northwest area of Chungnam. METHODS: We have reviewed 40,112 adults who...
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Status of Primary Liver Cancer Found through Routine Health Check-up

Lee C, Yang JI, Byun HJ, Kang JM, Choi S, Yim JY

This study aimed to investigate the status of primary liver cancers found through a routine health check-up. The data of subjects who were diagnosed with primary liver cancer for the...
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The relationship between virological characteristics of hepatitis C virus (HCV) and reactivity to the regional specific proteins of HCV

Yoon SK, Park YM, Byun BH, Bae SH, Yang JM, Ahn BM, Lee YS, Lee CD, Sun HS, Kim BS

  • KMID: 759502
  • Korean J Intern Med.
  • 2000 Jul;15(2):109-116.
BACKGROUND: Although the polyproteins of hepatitis C virus(HCV) are processed and formed in nearly equimolar amounts, individual functional proteins have a discrepancy...
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A Case of Small Bowel Diffuse Large B-cell Lymphoma Mimicking Crohn's Disease

Koo TH, Choi WJ, Han SH, Kim SY, Lee JH

A 66-year-old male with dyspepsia and weight loss was referred to our hospital for evaluation. On laboratory examination, anti-saccharomyces cerevisiae (ASCA)-IgA was positive and iron deficiency anemia was present. PET/CT...
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Association of Polymorphism in MicroRNA 604 with Susceptibility to Persistent Hepatitis B Virus Infection and Development of Hepatocellular Carcinoma

Cheong JY, Shin HD, Cho SW, Kim YJ

MicroRNA polymorphisms may be associated with carcinogenesis or immunopathogenesis of infection. We evaluated whether the mircoRNA-604 (miR-604) polymorphism can affect the persistence of hepatitis B virus (HBV) infection, and the...
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Delivery of Factor VIII Gene into Skeletal Muscle Cells Using Lentiviral Vector

Jeon HJ, Oh TK, Kim OH, Kim ST

PURPOSE: This study was designed to investigate whether transduction of lentiviral vectors (LV) carrying human coagulation factor VIII (hFVIII) cDNA into skeletal muscle could increase circulating hFVIII concentrations. MATERIALS AND...
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A Survey on the Status of Hepatitis E Virus Infection Among Slaughterhouse Workers in South Korea

Kim BS, Lim HS, Lee K, Min YS, Yoon YS, Jeong HS

OBJECTIVES: The seroprevalence of hepatitis E virus (HEV) among high-risk groups overseas is high, but studies in these groups are rare in South Korea. We conducted the present study from...
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