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The production and characterization of anti-Naegleria fowleri monoclonal antibodies

Ryu JS, Im KI

Naegleria fowleri, a free-living amoeba commonly found in moist soil and fresh water, enters the body via the nasal mucosa and migrates along the olfactory nerve to the brain, where...
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Diagnosis and epidemiology of toxoplasmosis in Korea

Choi WY

Toxoplasma gondii can cause congenital as well as postnatal toxoplasmosis in humans and animals, and thereby elicit various kinds and grades of clinical manifestations. In the human host, especially the...
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The protective effects of monoclonal antibodies in mice from Naegleria fowleri infection

Soh EY, Shin HJ, Im K

Protective effects of monoclonal antibodies against N. fowleri were comparatively studied. BALB/c mice were treated with two types of monoclonal antibodies, Nf 2 and Nf 154, before and after the...
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Cell-mediated immunity in experimental amoebic meningoencephalitis

Im KI, Chung PR, Kim TU

Cell-mediated and humoral immune reactions in mice infected with pathogenic Acanthamoeba culbertsoni were observed according to the period of time after amoebic infection by intranasal inoculation. The degrees of blastogenesis...
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Detection of antibodies in serum and cerebrospinal fluid to Toxoplasma gondii by indirect latex agglutination test and enzyme-linked immunosorbent assay

Choi WY, Nam HW, Youn JH, Kim DJ, Kong Y, Kang SY, Cho SY

Sensitivity of anti-Toxoplasma antibody (IgG) test by enzyme-linked immunosorbent assay (ELISA) was evaluated in comparison with indirect latex agglutination (ILA) using 2,016 paired human samples of serum and cerebrospinal fluid...
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Detection of IgG and IgM antibodies with ELISA technique in human trichomoniasis

Yi MR, Shin MH, Leem MH, Ryu JS, Ahn MH, Min DY

The direct wet mount examination of vaginal secretion, widely applied for the diagnosis of Trichomonas vaginalis infection in woman patients, is rapid and economical, however, the sensitivity of this technique...
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Immunogenicity and protective efficacy of solubilized merozoite-enriched Theileria sergenti immunogens. I: Protection against homologous stabilate challenge

Baek BK, Choi IH, Kim BS, Hansen R, Kakoma I

Theileria sergenti were isolated from infected erythrocytes by hypotonic lysis, and soluble merozoite antigens were purified by sonication and differential centrifugation. The preparation contained 29, 34, 35 and 105 kD...
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Changes in blastogenic responses and antibody titers of mice infected with Toxoplasma gondii

Shin DW, Lee YH, Na YE, Kwon DS

This study was performed to observe the cell-mediated and humoral immune responses in mice which were infected with Beverley, Fukaya and ME49 strain of Toxoplasma gondii, respectively. The blastogenic responses...
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The effect of active immunization with Acanthamoeba culbertsoni in mice born to immune mother

Kong HH, Seo SA, Shin CO, Im KI

Acanthamoeba culbertsoni is a pathogenic free-living amoeba causing primary amoebic meningoencephalitis (PAME) in human and mouse. Several reports on the immune responses in mice with this amoebic infection have been...
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Toxoplasma antibody titers by indirect latex agglutination test in patients of Kangnam St. Mary's Hospital and Cheju Medical Center

Choi WY, Nam HW, Youn JH, Kim WS, Kim WK

Total 2,829 persons consisted of 1,019 general patients and 1,030 asthma-suspected patients who visited Kangnam St. Mary's Hospital and 780 general patients who visited Cheju Medical Center were examined for...
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Resistance to Naegleria fowleri infection passively acquired from immunized splenocyte, serum or milk

Ahn MH, Min DY

A pathogenic free-living amoeba, Naegleria fowleri, causes primary amoebic meningoencephalitis to human and experimental animals. This infection is rare, but the mortality is very high. Nowadays, drug treatment or active...
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Studies on the cell-mediated immunity in experimental Naegleria spp. infections

Lee SG, Shin HJ, Im KI

Observations were made on the differences in cell-mediated immune responses in the mice infected with strongly pathogenic Naegleria fowleri ITMAP 359, weakly pathogenic Naegleria jadini 0400, or non-pathogenic Naegleria gruberi...
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