- Single Center Experience of Five Diffuse Panbronchiolitis Patients Clinically Presenting as Severe Asthma
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Park KH, Park HJ, Lee JH, Park JW
- KMID: 2160614
- J Korean Med Sci.
- 2015 Jun;30(6):823-828.
- doi: 10.3346/jkms.2015.30.6.823
Diffuse panbronchiolitis (DPB) is a bronchiolitis affecting the whole lung fields which can be treated by macrolide. Especially East Asian patients are more susceptible to diffuse panbronchiolitis. As asthma and... -
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- The effects of low dose leukotriene receptor antagonist therapy on airway remodeling and cysteinyl leukotriene expression in a mouse asthma model
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Muz MH, Deveci F, Bulut Y, Ilhan N, Yekeler H, Turgut T
- KMID: 1111403
- Exp Mol Med.
- 2006 Apr;38(2):109-118.
Airway structural changes that occur in patients with asthma in response to persistent inflammation are termed airway remodeling. The cysteinyl leukotrienes (LTC4, D4 and E4) are known to play important... -
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- The Soluble Tumor Necrosis Factor-Alpha Receptor Suppresses Airway Inflammation in a Murine Model of Acute Asthma
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Nam HS, Lee SY, Kim SJ, Kim JS, Kwon SS, Kim YK, Kim KH, Moon HS, Song JS, Park SH, Kim SC
- KMID: 1758619
- Yonsei Med J.
- 2009 Aug;50(4):569-575.
- doi: 10.3349/ymj.2009.50.4.569
PURPOSE: Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine that has been implicated in many aspects of the airway pathology in asthma. TNF-alpha blocking strategies are now being tried in... -
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- The Effect of CpG-Oligodeoxynucleotides with Different Backbone Structures and 3' Hexameric Deoxyriboguanosine Run Conjugation on the Treatment of Asthma in Mice
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Chang YS, Kim YK, Kwon HS, Park HW, Min KU, Kim YY, Cho SH
- KMID: 1782007
- J Korean Med Sci.
- 2009 Oct;24(5):860-866.
- doi: 10.3346/jkms.2009.24.5.860
CpG-Oligodeoxynucleotide (ODN) has two backbones. Phosphorothioate backbone (PS) shows a strong immunostimulating effect while phosphodiester (PE) shows little in vivo. 3' hexameric deoxyriboguanosine-run (3' dG6-run) conjugation to PE CpG-ODN has... -
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