- Angiotensin II stimulates proliferation of adventitial fibroblasts cultured from rat aortic explants
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Kim DK, Huh JE, Lee SH, Hong KP, Park JE, Seo JD, Lee WR
- KMID: 646015
- J Korean Med Sci.
- 1999 Oct;14(5):487-496.
- doi: 10.3346/jkms.1999.14.5.487
It has been proposed that the local renin-angiotensin system is activated in the adventitia after vascular injury. However, the physiological role of Angiotensin II (Ang II) in the adventitia has... -
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- Role of Inflammation in the Pathogenesis of Arterial Stiffness
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Park S, Lakatta EG
- KMID: 1120190
- Yonsei Med J.
- 2012 Mar;53(2):258-261.
- doi: 10.3349/ymj.2012.53.2.258
Increased arterial stiffness is an independent predictor of cardiovascular disease independent from blood pressure. Recent studies have shed new light on the importance of inflammation on the pathogenesis of arterial... -
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- Angiotensin II-induced aortic ring constriction is mediated by phosphatidylinositol 3-kinase/L-type calcium channel signaling pathway
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Do KH, Kim MS, Kim JH, Rhim BY, Lee WS, Kim CD, Bae SS
- KMID: 1119322
- Exp Mol Med.
- 2009 Aug;41(8):569-576.
- doi: 10.3858/emm.2009.41.8.062
Angiotensin II (AngII) is a crucial hormone that affects vasoconstriction and exerts hypertrophic effects on vascular smooth muscle cells. Here, we showed that phosphatidylinositol 3-kinase-dependent calcium mobilization plays pivotal roles... -
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- NADPH oxidase mediated oxidative stress in hepatic fibrogenesis
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Paik YH, Brenner DA
- KMID: 1792602
- Korean J Hepatol.
- 2011 Dec;17(4):251-257.
- doi: 10.3350/kjhep.2011.17.4.251
NADPH oxidase (NOX) is a multicomponent enzyme complex that generates reactive oxygen species (ROS) in response to a wide range of stimuli. ROS is involved as key secondary messengers in... -
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