- Angiotensin II receptor blocker attenuates overexpression of vascular endothelial growth factor in diabetic podocytes
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Lee EY, Shim MS, Kim MJ, Hong SY, Shin YG, Chung CH
- KMID: 755667
- Exp Mol Med.
- 2004 Feb;36(1):65-70.
VEGF expressed in glomerular podocytes, is known to increase vascular permeability to macromolecules. Angiotensin II can stimulate the release of VEGF, and the protective effects of angiotensin II antagonist against... -
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- Sodium tanshinone IIA sulfonate attenuates angiotensin II-induced collagen type I expression in cardiac fibroblasts in vitro
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Yang L, Zou XJ, Gao X, Chen H, Luo JL, Wang ZH, Liang QS, Yang GT
- KMID: 1058025
- Exp Mol Med.
- 2009 Jul;41(7):508-516.
- doi: 10.3858/emm.2009.41.7.056
Cardiac fibrosis occurs after pathological stimuli to the cardiovascular system. One of the most important factors that contribute to cardiac fibrosis is angiotensin II (Ang II). Accumulating studies have suggested... -
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- Sodium tanshinone IIA sulfonate depresses angiotensin II-induced cardiomyocyte hypertrophy through MEK/ERK pathway
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Yang L, Zou X, Liang Q, Chen H, Feng J, Yan L, Wang Z, Zhou D, Li S, Yao S, Zheng Z
- KMID: 1103682
- Exp Mol Med.
- 2007 Feb;39(1):65-73.
Cardiomyocyte hypertrophy is a major cause of morbidity and mortality worldwide. The aim of this study is to determine the effects of sodium tanshinone IIA sulfonate (STS) on cardiomyocyte hypertrophy... -
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