- Angiopoietins in Diabetic Nephropathy
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Lee EY, Gil HW, Yang JO, Koh JH, Chung CH, Hong SY
- KMID: 2079686
- Korean J Nephrol.
- 2007 May;26(3):311-319.
PURPOSE: It has been reported that angiopoietins and Tie-2 receptor play an important role in the maintenance of glomerular filtration barrier in various glomerulonephritis models. We studied the role of... -
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- Identification of Novel Drug Targets for the Treatment of Diabetic Retinopathy
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Uemura A
- KMID: 2174261
- Diabetes Metab J.
- 2013 Aug;37(4):217-224.
- doi: 10.4093/dmj.2013.37.4.217
Vision loss in diabetic retinopathy (DR) is attributable to retinal vascular disorders that result in macular edema and neoangiogenesis. In addition to laser photocoagulation therapy, intraocular injections of antivascular endothelial... -
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- Expression of Angiopoietin-1 & -2 mRNA in Invasive Cervical Cancer
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Yoo MY, Moon HS, Park HM, Chung HW, Kim SC
- KMID: 1980129
- Korean J Gynecol Oncol Colposc.
- 2002 Sep;13(3):228-236.
OBJECTIVE: The angiopoietins (Ang) are recently described as one of growth factors for vascular endothelium. This study was aimed to investigate the Ang-1 and Ang-2 mRNA expression between in cervical... -
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- Expressions and Clinical Significances of Angiopoietin-1, Angiopoietin-2, and Tie-2 Receptor in Patients With Colorectal Cancer
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Hong S, Jung HI, Ahn TS, Kim HJ, Lee KT, Baek MJ, Bae SB
- KMID: 2377384
- Ann Coloproctol.
- 2017 Feb;33(1):9-15.
- doi: 10.3393/ac.2017.33.1.9
PURPOSE: Angiopoietin-1 (Ang-1) plays a crucial role in vascular and hematopoietic development, mainly through its cognate receptor, Tie-2. Increased levels of Ang-2 have been shown to be correlated with abnormal... -
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- Pathophysiology of Diabetic Retinopathy: The Old and the New
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Kusuhara S, Fukushima , Ogura S, Inoue N, Uemura A
- KMID: 2422781
- Diabetes Metab J.
- 2018 Oct;42(5):364-376.
- doi: 10.4093/dmj.2018.0182
Vision loss in diabetic retinopathy (DR) is ascribed primarily to retinal vascular abnormalities—including hyperpermeability, hypoperfusion, and neoangiogenesis—that eventually lead to anatomical and functional alterations in retinal neurons and glial cells.... -
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