- Multiplex PCR for the Detection of Genes Encoding Aminoglycoside Modifying Enzymes and Methicillin Resistance among Staphylococcus Species
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Choi SM, Kim SH, Kim HJ, Lee DG, Choi JH, Yoo JH, Kang JH, Shin WS, Kang MW
- KMID: 1130030
- J Korean Med Sci.
- 2003 Oct;18(5):631-636.
- doi: 10.3346/jkms.2003.18.5.631
We developed multiplex polymerase chain reaction (PCR) to detect aac(6 ')/aph(2 "), aph(3 ')-IIIa, and ant(4 ')-Ia, the genes encoding the most clinically relevant amino-glycoside modifying enzymes (AME), and simultaneously,... -
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- Aminoglycoside Susceptibility Profiles of Enterobacter cloacae Isolates Harboring the aac(6')-Ib Gene
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Kim SY, Park YJ, Yu JK, Kim YS
- KMID: 1781692
- Korean J Lab Med.
- 2011 Oct;31(4):279-281.
- doi: 10.3343/kjlm.2011.31.4.279
The aminoglycoside 6'-N-acetyltransferases of type Ib (aac(6')-Ib) gene confers resistance to amikacin, tobramycin, kanamycin, and netilmicin but not gentamicin. However, some isolates harboring this gene show reduced susceptibility to amikacin.... -
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