- Neuroprotective mechanisms of dieckol against glutamate toxicity through reactive oxygen species scavenging and nuclear factor-like 2/heme oxygenase-1 pathway
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Cui Y, Amarsanaa , Lee JH, Rhim JK, Kwon JM, Kim SH, Park JM, Jung SC, Eun SY
- KMID: 2438086
- Korean J Physiol Pharmacol.
- 2019 Mar;23(2):121-130.
- doi: 10.4196/kjpp.2019.23.2.121
Glutamate toxicity-mediated mitochondrial dysfunction and neuronal cell death are involved in the pathogenesis of several neurodegenerative diseases as well as acute brain ischemia/stroke. In this study, we investigated the neuroprotective... -
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- Nobiletin attenuates neurotoxic mitochondrial calcium overload through K⺠influx and ΔΨ(m) across mitochondrial inner membrane
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Lee JH, Amarsanaa , Wu J, Jeon SC, Cui Y, Jung SC, Park DB, Kim SJ, Han SH, Kim HW, Rhyu IJ, Eun SY
- KMID: 2410095
- Korean J Physiol Pharmacol.
- 2018 May;22(3):311-319.
- doi: 10.4196/kjpp.2018.22.3.311
Mitochondrial calcium overload is a crucial event in determining the fate of neuronal cell survival and death, implicated in pathogenesis of neurodegenerative diseases. One of the driving forces of calcium... -
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