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The Effect of Glehnia Littoralis on Alpha-amanitin Induced Hepatotoxicity in a Murine Model

Ryu CY, Sun KH, Hong R, Park Y

PURPOSE: Glehnia littoralis has been reported to have several pharmacological properties but no in vivo reports describing the protective effects of this plant on α-amanitin-induced hepatotoxicity have been published. α-Amanitin...
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The Protective Effect of Green Tea Extract on Alpha-amanitin Induced Hepatotoxicity

An SH, Sun KH, Hong R, Lee BR, Park Y

PURPOSE: Alpha-amanitin induces potent oxidative stress and apoptosis, and may play a significant role in the pathogenesis of hepatotoxicity. This study examined the mechanisms of α-amanitin-induced apoptosis in vitro, and...
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In vitro Protective Effects of Glehnia Littoralis on Alpha-amanitin Induced Hepatotoxicity

Kim BH, Sun KH, Kim SP, Park Y

PURPOSE: Glehnia littoralis has been used to treat ischemic stroke, phlegm, cough, systemic paralysis, antipyretics and neuralgia. The pharmacological mechanisms of Glehnia littoralis include calcium channel block, coumarin derivatives, anticoagulation,...
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Chromatin Pattern-Dependent mRNA Synthesis in HeLa Cells and HeLa Tumors

Lee JH, Kang MW, Choi C, Juhng SW

  • KMID: 2172398
  • Chonnam Med J.
  • 2001 Dec;37(4):351-356.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in...
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Nucleolar translocalization of GRA10 of Toxoplasma gondii transfectionally expressed in HeLa cells

Ahn HJ, Kim S, Nam HW

Toxoplasma gondii GRA10 expressed as a GFP-GRA10 fusion protein in HeLa cells moved to the nucleoli within the nucleus rapidly and entirely. GRA10 was concentrated specifically in the dense fibrillar...
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