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Addition of Theophylline or Increasing the Dose of Inhaled Corticosteroid in Symptomatic Asthma: A Meta-Analysis of Randomized Controlled Trials

Wang Y, Lin K, Wang C, Liao X

PURPOSE: Low-dose theophylline has anti-inflammatory effects. The aim of this study was to evaluate the effects of adding theophylline compared with increasing the dose of inhaled corticosteroid (ICS) on symptomatic...
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A polymorphism in the histone deacetylase 1 gene is associated with the response to corticosteroids in asthmatics

Kim MH, Kim SH, Kim YK, Hong SJ, Min KU, Cho SH, Park HW

BACKGROUND/AIMS: Recent investigations suggest that histone deacetylase 1 (HDAC1) and HDAC2 may be target molecules to predict therapeutic responses to corticosteroids. We evaluated the effects of variation in HDAC1 and...
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