- The N- and C-terminal domains of parathyroid hormone-related protein affect differently the osteogenic and adipogenic potential of human mesenchymal stem cells
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Casado-Diaz A, Santiago-Mora R, Quesada JM
- KMID: 983981
- Exp Mol Med.
- 2010 Feb;42(2):87-98.
- doi: 10.3858/emm.2010.42.2.010
Parathyroid hormone-related protein (PTHrP) is synthesized by diverse tissues, and its processing produces several fragments, each with apparently distinct autocrine and paracrine bioactivities. In bone, PTHrP appears to modulate bone... -
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- Inhibition of mouse brown adipocyte differentiation by second-generation antipsychotics
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Oh JE, Cho YM, Kwak SN, Kim JH, Lee KW, Jung H, Jeong SW, Kwon OJ
- KMID: 1389734
- Exp Mol Med.
- 2012 Sep;44(9):545-553.
Brown adipose tissue is specialized to burn lipids for thermogenesis and energy expenditure. Second-generation antipsychotics (SGA) are the most commonly used drugs for schizophrenia with several advantages over first-line drugs,... -
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- Antiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model
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Moon MH, Jeong JK, Lee JH, Park YG, Lee YJ, Seol JW, Park SY
- KMID: 1506224
- Exp Mol Med.
- 2012 Oct;44(10):603-614.
Higher levels of body fat are associated with an increased risk for development numerous adverse health conditions. FTY720 is an immune modulator and a synthetic analogue of sphingosine 1-phosphate (S1P),... -
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- Neuronal maturation in the hippocampal dentate gyrus via chronic oral administration of Artemisa annua extract is independent of cyclooxygenase 2 signaling pathway in diet-induced obesity mouse model
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Baek HK, Kim PS, Song JA, Choi DH, Kim DE, Oh SI, Park SK, Kim SJ, Song KD, Hwang IK, Seo HS, Yi SS
- KMID: 2412564
- J Vet Sci.
- 2017 Jun;18(2):119-127.
- doi: 10.4142/jvs.2017.18.2.119
Recently, we reported that Artemisia annua (AA) has anti-adipogenic properties in vitro and in vivo. Reduction of adipogenesis by AA treatment may dampen systemic inflammation and protect neurons from cytokine-induced... -
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- Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte
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Choi BH, Ahn IS, Kim YH, Park JW, Lee SY, Hyun CK, Do MS
- KMID: 1115937
- Exp Mol Med.
- 2006 Dec;38(6):599-605.
Berberine (BBR), an isoquinoline alkaloid, has a wide range of pharmacological effects, yet its exact mechanism is unknown. In order to understand the anti-adipogenic effect of BBR, we studied the... -
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