- The Protective Effect of Mannitol and Methylprednisolone in the Acute Focal Cerebral Ischemia in Cats
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Shin KM
- KMID: 2170822
- Ewha Med J.
- 1988 Dec;11(4):283-297.
- doi: 10.12771/emj.1988.11.4.283
It is the purpose of the this experimental study to investigate the protective effect of pretreatment of mannitol and methylprednisolone(MP) on the changes of the high-energy metabolites(nucleotides ; derivatives of... -
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- The Effects of Sodium Nitroprusside on Platelet Aggregation Function during Deliberate Hypotensive Anesthesia
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Kang WJ, Choi YK, Lee DI
- KMID: 1934340
- Korean J Anesthesiol.
- 1995 Apr;28(4):561-567.
- doi: 10.4097/kjae.1995.28.4.561
Sodium nitroprusside is reported to inhibite platelet aggregation. We studied the effects of sodium nitroprusside on platelet aggregation function were in 30 adult patients undergoing spine surgery with enflurane anesthesia.... -
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- Ticlopidine Induced Bullous Pemphigoid
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Lee HY, Baek JO, Lee JR, Kim M, Kim SC, Roh JY
- KMID: 2247764
- Korean J Dermatol.
- 2009 Sep;47(9):1019-1023.
Bullous pemphigoid (BP) is an acquired autoimmune disease that's characterized by subepidermal vesicles and bullae. The etiology for BP is mostly idiopathic, but numerous observations have suggested the role of... -
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- Mitochondrial Metabolic Inhibition and Cardioprotection
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Lee SR, Han J
- KMID: 2377453
- Korean Circ J.
- 2017 Mar;47(2):168-170.
- doi: 10.4070/kcj.2016.0401
No abstract available. -
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- New Oral Antiplatelet Agents
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Kang MK, Chang K
- KMID: 2267821
- Korean J Med.
- 2013 Jul;85(1):10-14.
Antiplatelet agents play an essential role in the treatment of acute coronary syndrome (ACS). Aspirin and thienopyridines comprise the major classes of antiplatelet therapies demonstrated to be of benefit in... -
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- Effects of Adenosine 5'-Tetraphosphate on the Cardiac Activity*
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Lee JW, Park KS, Kong ID
- KMID: 2093590
- Korean Circ J.
- 1996 Jun;26(3):704-712.
- doi: 10.4070/kcj.1996.26.3.704
BACKGROUND: Adenosine 5'-tetraphosphate(ATPP), an endogenous nucleotide, is stored in cells and released into the extracellular space upon stimulation. Some of the biological responses to ATPP were reported, but characteristics of... -
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- The Effects of Sodium Nitroprusside on Platelet Aggregation Function during Intracranial Aneurysm Operation under Isoflurane Anesthesia
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Kang WJ, Son CH, Kim KS, Choi YK, Shin KI, Lee HJ
- KMID: 2237786
- Korean J Anesthesiol.
- 1996 Aug;31(2):217-223.
- doi: 10.4097/kjae.1996.31.2.217
BACKGROUND: The intravenous infusion of sodium nitroprusside is widely used as a means of producing deliberate hypotension in a variety of clinical situations. However, sodium nitroprusside reported to inhibit platelet... -
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- Apoptosis induced by adenosine 5'-trisphosphate in mouse leukemic cells
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Joo NY, Park KS, Chung HS, Lee JW
- KMID: 2285200
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):817-824.
Extracellular ATP elicits various biological responses and plays a significant role in physiological regulation. Recently, ATP-induced growth inhibitions were reported in some tumor cell lines, but these effects and mechanisms are not well... -
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- Asymmetrical distribution of P2Y nucleotide receptors in rabbit inner medullary collecting duct cells
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Woo JS, Jung JS, Kim YK
- KMID: 1917024
- Korean J Physiol Pharmacol.
- 2000 Aug;4(4):311-318.
We cultured the rabbit inner medullary collecting duct (IMCD) cells as monolayers on collagen-coated membrane filters, and investigated distribution of the P2Y receptors by analyzing nucleotide-induced short circuit current (Isc) responses. Exposure to... -
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- A Case of Clopidogrel-induced Neutropenia in Chronic Renal Failure
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Hong GY, Seon HG, Cheong JG, Joo SK, Kang MK, Lee JE, Kim JH, Koo SW, Park KM, Lee SY, Yang DH, Kim HJ
- KMID: 2080069
- Korean J Nephrol.
- 2010 Jan;29(1):153-157.
Clopidogrel, a thienopyridine derivative, is an anti-platelet agent that acts as an antagonist of the platelet adenosine diphosphate receptor and considered for essential prophylaxis for intracoronary stent thrombosis in the... -
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- Two cases of Ticlopidine-induced neutropenia in patients with cardiovascular disease
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Chae GS, Yoo HS, Jee JH, Lee JM, Ahn JS, Lee JA, Park YS, Doo YC, Han KR, Oh DJ, Rhim CY
- KMID: 2228923
- Korean Circ J.
- 1998 Feb;28(2):280-283.
- doi: 10.4070/kcj.1998.28.2.280
Ticlopidine is an antiplatelet agent used as a drug to prevent the recurrence of cerebral infarction or ischemic heart disease. Close attention has recently been paid to the superiority of... -
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- Platelet Aggregability in the Patients with Peripheral Vestibulopathy
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Kim YD, Cha CI, Cho JS, Lee KH, Ahn HY
- KMID: 1873952
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Oct;41(10):1259-1263.
BACKGROUND AND OBJECTIVES: Circulatory disturbance to vestibular organ has been regarded as one of the causes that bring about vertigo, and alteration of the platelet function is known to be... -
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- Effects of hydrocortisone and aminophylline on the aggregation of equine platelets in vitro
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Casella S, Giudice E, Giannetto , Marafioti , Piccione G
- KMID: 1067392
- J Vet Sci.
- 2011 Sep;12(3):215-219.
- doi: 10.4142/jvs.2011.12.3.215
The purpose of this study was to evaluate in vitro the effects of hydrocortisone and aminophylline on adenosine diphosphate (ADP)-induced platelet aggregation in horses. Blood samples from 30 healthy Thoroughbred... -
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- Oral antiplatelet agent hypersensitivity and cross-reactivity managed by successful desensitisation
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Chin N, Rangamuwa , Mariasoosai R, Carnes J, Thien F
- KMID: 2397068
- Asia Pac Allergy.
- 2015 Jan;5(1):51-54.
- doi: 10.5415/apallergy.2015.5.1.51
Oral platelet aggregation inhibitors are widely used for the treatment and prevention of cardiovascular diseases, including coronary stent thrombosis. Premature discontinuation following percutaneous coronary intervention would pose a grave risk... -
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- Modulation of ATP-induced activation of the muscarinic K+ channel activity by protein kinase C
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Kim YM, Park HK, Han JH, Park CO, Hong SG
- KMID: 2071833
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):743-753.
The atrial acetylcholine-activated K+ (KACh) channel is gated by the pertussis toxin-sensitive inhibitory G (GK) protein. Earlier studies revealed that ATP alone can activate the KACh channel via transphosphorylation mediated by nucleoside-diphosphate kinase... -
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- Statins Inhibited the ADP-Stimulated Activation of Integrins alpha v beta5 and alpha v beta3 of Vascular Smooth Muscle Cells
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Joo SJ, Lee SC, Lee JW
- KMID: 2013164
- Korean Circ J.
- 2006 Dec;36(12):809-816.
- doi: 10.4070/kcj.2006.36.12.809
BACKGROUND AND OBJECTIVES: Integrins mediate the migration, adhesion and proliferation of vascular smooth muscle cells. Adenosine diphosphate (ADP) can activate vascular integrins. We assessed the hypothesis that 'statins inhibit the... -
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- Integrins Mediating Adhesion and Proliferation of ADP-stimulated Vascular Smooth Muscle Cells
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Joo SJ, Cha TJ, Lee JW
- KMID: 2093879
- Korean Circ J.
- 2003 May;33(5):409-419.
- doi: 10.4070/kcj.2003.33.5.409
BACKGROUND AND OBJECTIVES: Adenosine diphosphate (ADP), which is usually secreted from activated platelets, may activate integrins on vascular smooth muscle cells, resulting in adhesion and proliferation. Integrins, mediating the ADP-stimulated... -
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- Three Cases of Ticlopidine-induced Cholestatic Hepatitis
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Kim JH, Kwon YJ, Kim JE, Woo KE, Kim YJ
- KMID: 2343006
- J Korean Neurol Assoc.
- 2002 Jul;20(4):434-436.
Ticlopidine hydrochloride is world-wide used antiplatelet agent that inhibit ADP pathway. Its clinical side effects are the change of the blood picture, allergic skin reaction and gastrointestinal symptoms. We report... -
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- Two Cases of Severe Neutropenia Associated with Ticlopidine
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Kim JT, Lee JG, Seo CJ, Shin EK
- KMID: 2434663
- Korean Circ J.
- 1999 Jul;29(7):746-750.
Ticlopidine is a powerful inhibitor of platelet aggregation which is induced by adenosine diphosphate. Ticlopidine has been shown to be effective in reducing combined stroke, myocardial infarction, reocclusion of coronary... -
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- Characterization of the distinct mechanism of agonist-induced canine platelet activation
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Chaudhary , Kim S
- KMID: 2434772
- J Vet Sci.
- 2019 Jan;20(1):10-15.
- doi: 10.4142/jvs.2019.20.1.10
Platelet activation has a major role in hemostasis and thrombosis. Various agonists including adenosine diphosphate (ADP) and thrombin interact with G protein-coupled receptors (GPCRs) which transduce signals through various G... -
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