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PURPOSE: The phosphodiesterase 5 inhibitor sildenafil has antinociceptive effects, mediated by an increase in cGMP. This study examined the role of spinal adenosine and serotonin receptors played in the antinociceptive...
Adenosine deaminase (ADA), an enzyme essential for the differentiation of lymphoid cells, has been used for monitoring diseases with altered immunity. The purpose of this study was to investigate the...
Kim HS, Jeong SY, Lee JH, Kim BE, Kim JW, Jeong SW, Kim IK
KMID: 755099
Exp Mol Med.
2000 Dec;32(4):197-203.
3-Deazaadenosine (DZA), one of the potent inhibitors of S-adenosylhomocysteine
hydrolase, is known to possess several biological properties including an
induction of apoptosis. To evaluate a possibility that DZA...