- Activin A Stimulates Mouse APCs to Express BAFF via ALK4-Smad3 Pathway
-
Kim JH, Seo GY, Kim PH
- KMID: 1449810
- Immune Netw.
- 2011 Aug;11(4):196-202.
- doi: 10.4110/in.2011.11.4.196
BACKGROUND: B cell-activating factor belonging to the TNF family (BAFF) is primarily expressed by macrophages and dendritic cells, and stimulates B cell proliferation, differentiation, survival, and Ig production. In the... -
- CITED
-
- Close
- SHARE
-
- Close
- Activin Receptor-Like Kinase 5 Inhibitor Attenuates Fibrosis in Fibroblasts Derived from Peyronie's Plaque
-
Jang JH, Ryu JK, Suh JK
- KMID: 1988823
- Korean J Urol.
- 2012 Jan;53(1):44-49.
- doi: 10.4111/kju.2012.53.1.44
PURPOSE: Transforming growth factor-beta1 (TGF-beta1) is the key fibrogenic cytokine associated with Peyronie's disease (PD). The aim of this study was to determine the antifibrotic effect of 3-((5-(6-Methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl) methyl)benzamide (IN-1130),... -
- CITED
-
- Close
- SHARE
-
- Close
- Transforming Growth Factor-beta Type I Receptor Inhibitor Induces Functional and Morphologic Recovery in a Rat Model of Erectile Dysfunction and Cavernous Fibrosis
-
Ryu JK, Oh SM, Jin HR, Song KM, Kwon MH, Kim DK, Suh JK
- KMID: 2298805
- Korean J Androl.
- 2012 Apr;30(1):23-30.
- doi: 10.5534/kja.2012.30.1.23
PURPOSE: To examine the effectiveness of small-molecule inhibitor of transforming growth factor-beta (TGF-beta) type I receptor, an activin receptor-like kinase 5 (ALK5), on erectile dysfunction (ED) in a rat model... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of IN-1130, a Novel Transforming Growth Factor-beta Type I Receptor Kinase (ALK5) Inhibitor, on a Rat Model of Peyronie's Disease Induced by Repeated Intratunical Injections of Fibrin
-
Piao S, Tumurbaatar M, Oh JH, Park SH, Suh JK, Ryu JK
- KMID: 2298783
- Korean J Androl.
- 2009 Aug;27(2):82-88.
PURPOSE: Transforming growth factor-beta1 (TGF-beta1) has been known to be involved in the pathogenesis of Peyronie's disease (PD). In the present study, we investigated the therapeutic effect of IN-1130, a... -
- CITED
-
- Close
- SHARE
-
- Close
- ACVR1 Gene Mutation in Sporadic Korean Patients with Fibrodysplasia Ossificans Progressiva
-
Lee DY, Cho TJ, Lee HR, Park MS, Yoo WJ, Chung CY, Choi IH
- KMID: 1779159
- J Korean Med Sci.
- 2009 Jun;24(3):433-437.
- doi: 10.3346/jkms.2009.24.3.433
Fibrodysplasia ossificans progressiva (FOP; OMIM 135100) is a rare but extremely disabling genetic disorder of the skeletal system, and is characterized by the progressive development of ectopic ossification of skeletal... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical Features and Mutations in the ENG, ACVRL1, and SMAD4 genes in Korean Patients with Hereditary Hemorrhagic Telangiectasia
-
Lee ST, Kim JA, Jang SY, Kim DK, Do YS, Suh GY, Kim JW, Ki CS
- KMID: 1794409
- J Korean Med Sci.
- 2009 Feb;24(1):69-76.
- doi: 10.3346/jkms.2009.24.1.69
Hereditary hemorrhagic telangiectasia (HHT) is an inherited disorder that is characterized by abnormal communication between the arteries and veins in the skin, mucosa, and various organs. HHT has been reported... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression and Localization of the Transforming Growth Factor-beta Type I receptor and Smads in Preneoplastic Lesions during Chemical Hepatocarcinogenesis in Rats
-
Park DY, Lee CH, Sol MY, Suh KS, Yoon SY, Kim JW
- KMID: 648902
- J Korean Med Sci.
- 2003 Aug;18(4):510-519.
- doi: 10.3346/jkms.2003.18.4.510
Little is known about the involvement of Smad-related molecules in the regulation of the Transforming Growth Factor (TGF)-beta signaling pathway during hepatocarcinogenesis, particularly with respect to preneoplastic lesions of a... -
- CITED
-
- Close
- SHARE
-
- Close
- Osler-Weber-Rendu disease presenting with hepatocellular carcinoma: radiologic and genetic findings
-
Lee JH, Lee YS, Kim PN, Lee BH, Kim GW, Yoo HW, Heo NY, Lim YS, Lee HC, Chung YH, Suh DJ
- KMID: 1792610
- Korean J Hepatol.
- 2011 Dec;17(4):313-318.
- doi: 10.3350/kjhep.2011.17.4.313
This is a case report of a 68-year-old man with hepatocellular carcinoma (HCC) accompanied by hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu disease, and hepatic vascular malformation. HHT is... -
- CITED
-
- Close
- SHARE
-
- Close
