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Isozyme electrophoresis patterns of the liver fluke, Clonorchis sinensis from Kimhae, Korea and from Shenyang, China

Park GM, Yong TS, Im K, Lee KJ

An enzyme analysis of the liver fluke, Clonorchis sinensis from Kimhae, Korea and from Shenyang, China was conducted using a horizontal starch gel electrophoresis in order to elucidate their genetic...
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Induction of Apoptosis of Bladder Cancer Cells by Zinc-Citrate Compound

Hong SH, Choi YS, Cho HJ, Lee JY, Hwang TK, Kim SW

  • KMID: 2316135
  • Korean J Urol.
  • 2012 Nov;53(11):800-806.
PURPOSE: Zinc is one of the trace minerals in the body and is known to have an anticancer effect by inducing apoptosis in prostate cancer. We aimed to investigate the...
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Inactivation of Aconitase by Tetrahydrobiopterin in DArgic Cells: Relevance to PD

Yoon NS, Cho Y, Lee SY, Choi HJ, Hwang O

Oxidative damage is thought to be a major cause of the progression of dopamine (DA)rgic neurodegeneration as in Parkinson's disease. We have previously reported that tetrahydrobiopterin (BH4), an endogenous molecule...
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Analysis of Spatial and Temporal Protein Expression in the Cerebral Cortex after Ischemia-Reperfusion Injury

Chen YH, Chiang YH, Ma HI

BACKGROUND AND PURPOSE: Hypoxia, or ischemia, is a common cause of neurological deficits in the elderly. This study elucidated the mechanisms underlying ischemia-induced brain injury that results in neurological sequelae. METHODS:...
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Antiproliferative and Apoptotic Effects of Zinc-Citrate Compound (CIZAR(R)) on Human Epithelial Ovarian Cancer Cell (OVCAR3)

Lee YS, Kim JD, Park LO, Bae SN

  • KMID: 2272841
  • Korean J Obstet Gynecol.
  • 2006 Jul;49(7):1427-1436.
OBJECTIVE: Human seminal plasma has diverse biological activities including cytotoxic effect. It contains high concentrations of zinc and citric acid. Zinc inhibits several carcinoma cell growths through induction of cell...
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Ascorbic acid extends replicative life span of human embryonic fibroblast by reducing DNA and mitochondrial damages

Hwang WS, Park SH, Kim HS, Kang HJ, Kim MJ, Oh SJ, Park JB, Kim J, Kim SC, Lee JY

  • KMID: 2313302
  • Nutr Res Pract.
  • 2007 Jun;1(2):105-112.
Ascorbic acid has been reported to extend replicative life span of human embryonic fibroblast (HEF). Since the detailed molecular mechanism of this phenomenon has not been investigated, we attempted to...
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The effect of cytokines and endotoxin on the nitric oxide production and its relation to mitochondrial aconitase activity in cultured rat lung microvascular endothelial cells

Jang SH, Chang J, Park JH, Kim SK, Kim SJ, Kim SK, Lee WY, Markewitz , Michael JR

  • KMID: 2306304
  • Korean J Med.
  • 1999 Feb;56(2):174-181.
OBJECTIVE: Both constitutive and inducible forms of nitric oxide synthase exist in endothelial cells. Disorders that produce acute lung injury frequently release endotoxin and cytoknes, such as interferon(IFNgamma) and tumor necrosis factor...
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