- Gene Expression in Rat Hearts Following Oral Administration of a Single Hepatotoxic Dose of Acetaminophen
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Jin SM, Kil HR, Park K, Noh CI
- KMID: 1779703
- Yonsei Med J.
- 2012 Jan;53(1):172-180.
- doi: 10.3349/ymj.2012.53.1.172
PURPOSE: Toxicity caused by acetaminophen and its toxic mechanisms in the liver have been widely studied, including effects involving metabolism and oxidative stress. However, its adverse effects on heart have... -
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- Time-course changes in the expression levels of miR-122, -155, and -21 as markers of liver cell damage, inflammation, and regeneration in acetaminophen-induced liver injury in rats
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Park HK, Jo W, Choi HJ, Jang S, Ryu JE, Lee HJ, Lee H, Kim H, Yu ES, Son WC
- KMID: 2363334
- J Vet Sci.
- 2016 Mar;17(1):45-51.
- doi: 10.4142/jvs.2016.17.1.45
Drug-induced liver injury (DILI) is a significant threat to patient health and a major concern during drug development. Recently, multiple circulating microRNAs (miRNAs) have been reported to be potential biomarkers... -
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