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Clinical effect of abiraterone acetate in Korean patients with metastatic castration-resistant prostate cancer according to duration of androgen deprivation therapy

Kim KB, Jo JK, Ahn S, Lee S, Jeong SJ, Hong SK, Byun SS, Lee SE

PURPOSE: Few data are available concerning the clinical outcome of abiraterone acetate treatment in patients with metastatic castration-resistant prostate cancer (mCRPC) in terms of the duration of androgen deprivation therapy...
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Limited Expression of Cytochrome P450 17alpha-Hydroxylase/17,20-Lyase in Prostate Cancer Cell Lines

Jeong CW, Yoon CY, Jeong SJ, Hong SK, Byun SS, Lee SE

  • KMID: 2315445
  • Korean J Urol.
  • 2011 Jul;52(7):494-497.
PURPOSE: Cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17A1) is a key enzyme in the androgen biosynthesis pathway. CYP17A1 has been focused on because of the promising results of a potent CYP17A1 inhibitor in...
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