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Effects of cyclic nucleotides and glipizide on the cardiovascular response of baclofen in the rats

Shin IC, Koh HC, Ha JH

  • KMID: 2285182
  • Korean J Physiol Pharmacol.
  • 1997 Dec;1(6):647-655.
The purpose of present study is to investigate the influence of a spinal gamma-aminobutyric acid B(GABA|B) receptor on a central regulation of blood pressure (BP) and heart rate (HR), and to define its...
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cAMP induction by ouabain promotes endothelin-1 secretion via MAPK/ERK signaling in beating rabbit atria

Peng LQ, Li P, Zhang QL, Hong L, Liu LP, Cui X, Cui BR

Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the Na(+)-K(+)-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase...
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The role of dependent pathway in eosinophil apoptosis

Ki SY, Jeon KW, Lee MR, Uh ST, Kim YH, Park CS, Chung IY

  • KMID: 2286031
  • J Asthma Allergy Clin Immunol.
  • 1999 Oct;19(5):667-684.
BACKGROUND: Interleukin-5 (IL-5), IL-3, and GM-CSF are known to prolong the survival of eosinophils, and IL-5 has the most potent effect on eosinophil survivaL It is also known that divergent signals induce...
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Interaction of forskolin with the effect of N-6-cyclopentyladenosine on norepinephrine release in rat hippocampus

Choi BK, Kim DK, Son Y, Yang UJ

  • KMID: 2285166
  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):225-231.
As it has been reported that the depolarization-induced norepinephrine (NE) release is modulated by activation of presynaptic A-1-adenosine heteroreceptor and various lines of evidence indicate the involvement of adenylate cyclase system in A-1-adenosine...
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Effect of Somatostatin on Cholecystokinin-Induced Amylase Release in Rat Pancreatic Acini

Rhie DJ, Choi WS, Yi SY, Yoon SH, Hahn SJ, Sim SS, Kim MS, Jo YH

  • KMID: 2304683
  • Korean J Gastroenterol.
  • 1998 Dec;32(6):773-781.
BACKGROUND/AIMS: The inhibitory effect of somatostatin (SS) on cholecystokinin (CCK)-induced amylase release and the role of intracellular cAMP in this process were investigated. METHODS: Pancreatic acini were isolated from rat pancreas...
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Pituitary Adenylate Cyclase-activating Polypeptide Inhibits Pacemaker Activity of Colonic Interstitial Cells of Cajal

Wu MJ, Kee KH, Na J, Kim SW, Bae Y, Shin DH, Choi S, Jun JY, Jeong HS, Park JS

This study aimed to investigate the effect of pituitary adenylate cyclase-activating peptide (PACAP) on the pacemaker activity of interstitial cells of Cajal (ICC) in mouse colon and to identify the...
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Genome-wide expression profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray.

Park GH, Choe JG, Choo HJ, Park YG, Sohn JW, Kim MK

  • KMID: 1380226
  • Exp Mol Med.
  • 2002 Jul;34(3):184-193.
Previous reports raised question as to whether 8-chloro-cyclic adenosine 3,5-monophosphate (8-Cl-cAMP) is a prodrug for its metabolite, 8-Cl-adenosine which exerts growth inhibition in a broad spectrum of cancer cells. The...
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Regulatory mechanisms of angiotensin II on the Na+/H+ antiport system in rabbit renal proximal tubule cells. I. Stimulatory effects of ANG II on Na+ uptake

Han HJ, Koh HJ, Park SH

  • KMID: 2071513
  • Korean J Physiol Pharmacol.
  • 1997 Aug;1(4):413-423.
The importance of the kidney in the development of hypertension was first demonstrated by Goldblatt and his colleagues more than fifty years ago. Many hormones and other regulatory factors have been proposed to...
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Effect of Vasoactive Intestinal Peptide on the Necrotic or Apoptotic Neuronal Death in Murine Cortical Cell Cultures

Kim TS, Kim HW, Lee JK, Jung S, Kim JH, Kim SH, Kang SS, Lee JH, Lee KS, Kim JK

  • KMID: 2188503
  • J Korean Neurosurg Soc.
  • 1999 Oct;28(10):1398-1406.
OBJECTIVE: The purpose of this study was to examine the effects of VIP on the apoptotic neuronal death induced by serum deprivation and the necrotic(excitotoxic) neuronal death by the exposure...
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The effect of telomerase expression on the escape from M2 crisis in virus-transformed human retinal pigment epithelial cells.

Hwang JH, Park MI, Hwang YY, Yoo HJ, Mardon HJ

  • KMID: 1380227
  • Exp Mol Med.
  • 2002 Jul;34(3):194-200.
Integrins are heterodimeric glycoproteins that have been found to undergo dynamic temporal and spatial changes in the endometrium during the menstrual cycle and in early pregnancy. Specificity of integrins is...
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