- Effects of MK-801, CNQX, Cycloheximide and BAPTA-AM on Anoxic Injury of Hippocampal Organotypic Slice Culture
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Moon SH, Kwon TH, Park YK, Chung HS, Suh JK
- KMID: 1547771
- J Korean Neurosurg Soc.
- 2000 Aug;29(8):1008-1018.
No abstract available. -
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- In Vitro Effect of Carbamazepine, D-(-)-2-Amino-5-Phosphonopentanoic Acid and 6-Cyano-7-Nitroquinoxaline-Dione on Pentylenetetrazole-Induced Epileptiform Activity in Young Rat Visual Cortex
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Choi BJ
- KMID: 1851944
- J Korean Epilepsy Soc.
- 2005 Dec;9(2):137-142.
PURPOSE: Carbamazepine (CBZ) has little untoward effect in behavior, cognition and psychosocial aspects and commonly used in children. But, CBZ can sometimes worsen tonic-clonic seizures. The goal of the present... -
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- High K-induced Epileptiform Activity under GABA Antagonist and Carbamazepine in the Rat Visual Cortex
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Choi BJ
- KMID: 2329335
- J Korean Child Neurol Soc.
- 2006 May;14(1):16-23.
PURPOSE: The goal of this study was to investigate the effect of increase of K on the excitability of the visual cortex under GABA antagonist, carbamazepine(CBZP), 6-cyano-7-nitroquinoxaline-dione disodium(CNQX) and D-(-)-2-amino-5-phosphonopentanoic... -
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- Effect of Potassium, Bicuculline and CNQX on Epileptiform Activity Induced by Pilocarpine in the Rat Visual Cortex Slice
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Choi BJ, Kim YI
- KMID: 1636113
- J Korean Neurol Assoc.
- 2006 Dec;24(6):571-576.
BACKGROUND: The purpose of this study was to investigate the effect of potassium, bicuculline (BIC) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) on epileptiform activity induced by pilocarpine in the rat visual cortex slices.... -
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- Tetraethylammonium-induced Epileptiform Activity and its Modification by GABAA Antagonist in the Rat Visual Cortex
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Choi BJ
- KMID: 2329312
- J Korean Child Neurol Soc.
- 2005 Nov;13(2):137-143.
PURPOSE: The goal of this study was to investigate the effect of tetraethylammonium (TEA) on the excitability of visual cortex, and observe the induction of epileptiform activity. Also, it was... -
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- Bicuculline Induced Epileptiform Activity
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Choi BJ
- KMID: 2177013
- J Korean Child Neurol Soc.
- 2005 May;13(1):57-62.
PURPOSE: The goal of this study was to investigate the effects of bicuculline(BIC) on the excitability of visual cortex, observe the induction of epileptiform activity and define the characteristics of... -
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- Effect of NMDA Receptor Antagonist (APV)on the Toxicity Induced by Oxygen Radicals in Cultured Myocardial Cells
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Park OK, Oh JM, Kim JJ, Choi MK, Park ST, Chung YT
- KMID: 2283105
- Korean J Phys Anthropol.
- 1998 Dec;11(2):317-325.
Toxic effect of oxygen radicals and cardioprotective effect of N -methyl -D -aspartate (NMDA) receptor antagonists against xanthine oxidase (XO) and hypoxanthine (HX)-induced cardiotoxicity were measured in order to elucidate... -
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- Properties of Low Magnesium Induced Epileptiform Activity in Rat Visual Cortex Slices
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Choi BJ
- KMID: 2333402
- J Korean Epilepsy Soc.
- 2005 Jun;9(1):17-20.
PURPOSE: The goal of the present study was to investigate the effect of low magnesium on the excitability of visual cortex, observe the induction of epileptiform activity, and define the... -
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- Study on the [3H]Acetylcholine Release Induced by Oxygen-Glucose Deprivation in Rat Cerebral Cortical Slices
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Lee JJ, Kim KW, Seo MW, Kim YH
- KMID: 2342700
- J Korean Neurol Assoc.
- 1998 Aug;16(4):530-535.
BACKGROUND: It has been shown that cerebral ischemia alters brain acetylcholine (Ach) metabolism. In an attempt to elucidate the mechanisms for ischemia-induced release of Ach in vitro, the effects of... -
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- The Neuroprotective Effects of 6-cyano-7-nitroquinoxalin-2,3-dione (CNQX) Via Mediation of Nitric Oxide Synthase on Hypoxic-ischemic Brain Injury in Neonatal Rats
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Jung JE, Keum KH, Choi EJ, Kim JK, Chung HL, Kim WT
- KMID: 2188462
- J Korean Soc Neonatol.
- 2011 May;18(1):59-69.
- doi: 10.5385/jksn.2011.18.1.59
PURPOSE: Current studies have demonstrated the neuroprotective effects of 6-cyano-7-nitroquinoxalin-2,3-dione (CNQX) in many animal models of brain injury, including hypoxic-ischemic (HI) encephlopathy, trauma and excitotoxicity, but limited data are available... -
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- Excitotoxic Cell Death in Cultured Retinal Neurons
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Yoon YH, Shim MJ, Lee J
- KMID: 2123633
- J Korean Ophthalmol Soc.
- 1997 Nov;38(11):1987-1999.
We examined excitotoxicity, putatively a major mechanism of ischemic neuronal death, in primary rat retinal cultures. Retinal cultures were prepared from newborn rats (day 1 or 2). Exposure of these... -
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- Effect of MK801 and CNQX on Retinal Injury Induced by Ischemia, NMDA, or Kainate
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Choi JS, Gwag BJ, Yoon SK, Joo CK
- KMID: 2108525
- J Korean Ophthalmol Soc.
- 1998 Aug;39(8):1794-1800.
To examine the protection of retinal cell death by glutamate antagonists in vivo, this study was carried out in pressure-induced ischemia model. Firstly, we observed that ischemia resulted in the... -
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- N-methyl-D-aspartate (NMDA) and Non-NMDA Receptors are Involved in the Production and Maintenance of Nociceptive Responses by Intraplantar Injection of Bee Venom and Melittin in the Rat
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Kim JH, Shin HK
- KMID: 1600061
- Korean J Physiol Pharmacol.
- 2005 Jun;9(3):179-186.
Whole bee venom (WBV) and its major component, melittin, have been reported to induce long-lasting spontaneous flinchings and hyperalgesia. The current study was designed to elucidate the peripheral and spinal... -
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- Korean red ginseng excitation of paraventricular nucleus neurons via non-N-methyl-D-aspartate glutamate receptor activation in mice
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Shen Y, Bhattarai , Park SJ, Lee GS, Ryu PD, Han SK
- KMID: 2407616
- J Vet Sci.
- 2018 Mar;19(2):172-178.
- doi: 10.4142/jvs.2018.19.2.172
It has been reported that Korean red ginseng (KRG), a valuable and important traditional medicine, has varied effects on the central nervous system, suggesting its activities are complicated. The paraventricular... -
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- 4 Aminopyridine Induced Epileptiform Activity
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Choi BJ, Whang KT
- KMID: 2177014
- J Korean Child Neurol Soc.
- 2005 May;13(1):63-68.
PURPOSE: The goal of the present study was to investigate the effects of 4-aminopyridine(4-AP) on the excitability of visual cortex, observe the induction of epileptiform activity and define the characteristics... -
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- The Role of Peripheral N-Methyl-D-Aspartate (NMDA) Receptors in Freund's Complete Adjuvant Induced Mechanical Hyperalgesia in Rats
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Lim TH, Kang SS, Song JG, Choi Y
- KMID: 2091590
- Korean J Anesthesiol.
- 2000 Dec;39(6):S35-S40.
- doi: 10.4097/kjae.2000.39.6.S35
BACKGROUND: While the effects of excitatory amino acids have been characterized in the central nervous system, relatively little is known about their possible modulation of elements responsible for hyperalgesia within... -
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- Combined Application of Bicuculline and 4-Aminopyridine-Induced Epileptiform Activity are Resistant to Conventional Anticonvulsants and AMPA in Young Rat Visual Cortex
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Choi BJ
- KMID: 1816508
- J Korean Epilepsy Soc.
- 2006 Jun;10(1):35-40.
PURPOSE: The goal of the present study was to find out whether blockade of GABAergic synaptic transmission by bicuculline (BIC) in the presence of 4-aminopyridine (4-AP) would lead to expression... -
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- The Effect of Intrathecal NMDA and non-NMDA Receptor Antagonist on the Hyperalgesia Observed after Thermal Injury in the Rat
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Jun JH
- KMID: 2039879
- Korean J Anesthesiol.
- 1998 Apr;34(4):708-715.
- doi: 10.4097/kjae.1998.34.4.708
BACKGROUND: Previous reports have described NMDA antagonist reduced the nerve injury induced or inflammatory thermal hyperalgesia. This study evaluated the effects of spinally administered excitatory amino acid antagonists on the... -
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- Antihyperalgesic Effects of Intrathecal Gabapentin and CNQX, Non-NMDA Receptor Antagonist, in a Rat Model for Postoperative Pain
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Park HJ, Song JH, Song JM, Lee HS, Lee CS, Chung CK, Cha YD, Kim BS, Ryu JH
- KMID: 2104838
- J Korean Pain Soc.
- 2004 Dec;17(2):105-112.
- doi: 10.3344/jkps.2004.17.2.105
BACKGROUND: Although the descriptions of the pharmacological action mechanisms of gabapentin remain incomplete, gabapentin has been proven to provide analgesic effects in inflammatory, burn injury and neuropathic pain models. However,... -
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- Responsiveness of dendrites to the glutamate applied focally with pressure ejector and iontophoresis into hippocampal slices
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Kim JH, Shin HK, Chang HJ, Kim HY
- KMID: 1607134
- Korean J Physiol Pharmacol.
- 2001 Dec;5(6):457-466.
Glutamate is the most common excitatory amino acid in the brain. Responsiveness of dendrites to the glutamate greatly varies depending on the application sites. Especially, a point of the maximal... -
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