- TT Virus Detection Using Different PCR Primer Sets in Healthy and Infected Individuals with Hepatitis B or C Viruses
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Kim HS, Kim JS, Song W, Kang HJ, Lee KM
- KMID: 2224732
- Korean J Clin Microbiol.
- 2007 Apr;10(1):14-18.
BACKGROUND: TT virus (TTV) infection is highly prevalent in the general population and in the patients infected with hepatitis B virus (HBV) or hepatitis C vius (HCV). The aim of... -
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- Structure and Expression Analyses of SVA Elements in Relation to Functional Genes
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Kwon YJ, Choi Y, Eo J, Noh YN, Gim JA, Jung YD, Lee JR, Kim HS
- KMID: 2009107
- Genomics Inform.
- 2013 Sep;11(3):142-148.
- doi: 10.5808/GI.2013.11.3.142
SINE-VNTR-Alu (SVA) elements are present in hominoid primates and are divided into 6 subfamilies (SVA-A to SVA-F) and active in the human population. Using a bioinformatic tool, 22 SVA element-associated... -
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- Complete Nucleotide Sequence of Genomic RNA of a Large-Plaque Forming Porcine Reproductive and Respiratory Syndrome Virus PL97-1/LP1
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Lee YM
- KMID: 2055039
- J Bacteriol Virol.
- 2006 Dec;36(4):293-303.
- doi: 10.4167/jbv.2006.36.4.293
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important animal pathogens in swine industry worldwide. In this study, we isolated the large-plaque forming variant virus designated... -
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- Development of an efficient endothelial cell specific vector using promoter and 5' untranslated sequences from the human preproendothelin-1 gene
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Cho JY, Lim WC, Jang S, Lee YJ
- KMID: 1109315
- Exp Mol Med.
- 2003 Aug;35(4):269-274.
We report here, that a vector constructed based on ppET-1 gene promoter and 5' untranslated region induced a high level of gene expression in endothelial cells and the specificity is... -
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- Transcriptional Activity of Plasmodium Subtilisin-like Protease 2 (Pf-Sub2) 5'Untranslated Regions and Its Interaction with Hepatocyte Growth Factor
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Liao S, Liu Y, Jung SY, Cho PY, Zheng B, Park H
- KMID: 1104694
- Korean J Parasitol.
- 2010 Dec;48(4):291-295.
- doi: 10.3347/kjp.2010.48.4.291
The onset, severity, and ultimate outcome of malaria infection are influenced by parasite-expressed virulence factors and individual host responses to these determinants. In both humans and mice, liver injury is... -
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- Publicly Available Single Nucleotide Polymorphisms in Genes Possibly Susceptible to Antiepileptic Drug Resistance in Healthy Koreans
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Kim MK, Choi KH, Nam TS, Kim JT, Choi SM, Park MS, Kim BC, Cho KH
- KMID: 2065719
- J Korean Neurol Assoc.
- 2010 May;28(2):85-90.
BACKGROUND: The completion of the human genome project means that a high-quality reference sequence of the gene-rich portion of the human genome is now available. However, the strong influence of... -
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- Alternative splicing in 5'-untranslational region of STK-15 gene, encoding centrosome associated kinase, in breast cancer cell lines
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Shin SO, Lee KH, Kim JH, Baek SH, Park JW, Gabrielson EW, Kwon TK
- KMID: 755098
- Exp Mol Med.
- 2000 Dec;32(4):193-196.
Centrosomes maintain genomic stability by establishing the bipolar spindles during cell division and, execute accurate segregation of chromosomes during mitosis. In this study, we have demonstrated that there... -
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- Biochemical properties of full-length hepatitis C virus RNA-dependent RNA polymerase expressed in insect cells
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Choi HB, Kim YG, Oh JW
- KMID: 1119328
- Exp Mol Med.
- 2003 Dec;35(6):475-485.
The hepatitis C virus (HCV) RNA-dependent RNA polymerase, NS5B protein, is the key viral enzyme responsible for replication of the HCV viral RNA genome. Although several full-length and truncated forms... -
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- Expression of Exogenous Human Hepatic Nuclear Factor-1alpha by a Lentiviral Vector and Its Interactions with Plasmodium falciparum Subtilisin-Like Protease 2
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Liao S, Liu Y, Zheng B, Cho PY, Song HO, Lee YS, Jung SY, Park H
- KMID: 1715752
- Korean J Parasitol.
- 2011 Dec;49(4):431-436.
- doi: 10.3347/kjp.2011.49.4.431
The onset, severity, and ultimate outcome of malaria infection are influenced by parasite-expressed virulence factors as well as by individual host responses to these determinants. In both humans and mice,... -
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- Growth Differentiation Factor 5 (GDF5) Core Promoter Polymorphism Is Not Associated with Susceptibility to Osteoarthritis of the Knee in the Korean Population
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Cao Z, Lee HS, Song JH, Yoon JW, Park YK, Nam SW, Lee JY, Park WS
- KMID: 2277579
- Korean J Pathol.
- 2010 Aug;44(4):404-409.
BACKGROUND: Osteoarthritis (OA) is a common disease characterized by degenerating joint cartilage in the knee, hip, and hand. A functional single nucleotide polymorphism (SNP) +104T/C; rs143383 in the 5' untranslated... -
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- Molecular diagnosis of fragile X syndrome in a female child
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Jeong SY, Yang JA, Kim HJ
- KMID: 2184446
- J Genet Med.
- 2008 Jun;5(1):41-46.
PURPOSE: Fragile X syndrome (FXS) is the most common heritable cause of cognitive impairment. FXS is caused by hyperexpansion and hypermethylation of a polymorphic CGG trinucleotide repeat in the 5'... -
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- 5' CpG island methylation of p16 is associated with absence of p16 expression in glioblastomas
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Park SH, Jung KC, Ro JY, Kang GH, Khang SK
- KMID: 965879
- J Korean Med Sci.
- 2000 Oct;15(5):555-559.
- doi: 10.3346/jkms.2000.15.5.555
Recent evidence shows that transcriptional silencing as a consequence of hypermethylation of CpG islands is an important mechanism in the inactivation of p16INK4 tumor suppressor gene. This study is designed... -
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- Prevalence of PALB2 Germline Mutations in Early-onset and Familial Breast/Ovarian Cancer Patients from Pakistan
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Rashid MU, Khan FA, Muhammad N, Loya A, Hamann U
- KMID: 2454291
- Cancer Res Treat.
- 2019 Jul;51(3):992-1000.
- doi: 10.4143/crt.2018.356
PURPOSE: Partner and localizer of BRCA2 (PALB2) is a breast cancer susceptibility gene that plays an important role in DNA repair. This is the first study assessing the prevalence of... -
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- Molecular biological characterization of enterovirus variant isolated from patients with aseptic meningitis
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Jung YT, Kim GR, Paik SY
- KMID: 754995
- Exp Mol Med.
- 1998 Jun;30(2):101-107.
In Korea, there was a big outbreak of aseptic meningitis in 1993. Six clinical isolates of enterovirus were obtained from patients with aseptic meningitis and were identified as echovirus type 9 by... -
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- Prevalence of Hepatitis C Virus Infections and Distribution of Hepatitis C Virus Genotypes among Korean Blood Donors
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Oh DJ, Park YM, Seo YI, Lee JS, Lee JY
- KMID: 1381687
- Ann Lab Med.
- 2012 May;32(3):210-215.
- doi: 10.3343/alm.2012.32.3.210
BACKGROUND: Hepatitis C virus (HCV) remains a worldwide health-care burden. Prevalence rates vary and the distribution of genotypes depends on geographical location. Here, the recent prevalence of HCV infections and... -
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- WDR46 is a Genetic Risk Factor for Aspirin-Exacerbated Respiratory Disease in a Korean Population
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Pasaje CF, Bae JS, Park BL, Cheong HS, Kim JH, Uh ST, Park CS, Shin HD
- KMID: 1970708
- Allergy Asthma Immunol Res.
- 2012 Jul;4(4):199-205.
- doi: 10.4168/aair.2012.4.4.199
PURPOSE: The human WD repeat-containing protein 46 (WDR46; also known as C6orf11), located at the disease-relevant centromere side of the class II major histocompatibility complex region, is hypothesized to be... -
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- HMOX1 Gene Promoter Polymorphism is Not Associated with Coronary Artery Disease in Koreans
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Han SW, Song W, Kim HS, Shin KS, Kang H, Cho HC, Ki CS, Park MJ
- KMID: 1791947
- Ann Lab Med.
- 2014 Sep;34(5):337-344.
- doi: 10.3343/alm.2014.34.5.337
BACKGROUND: The heme oxygenase-1 gene (HMOX1) promoter polymorphisms modulate its transcription in response to oxidative stress. This study screened for HMOX1 polymorphisms and investigated the association between HMOX1 polymorphisms and... -
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- The Effect of Uteroglobin Exon 1, 5' Untranslated Region Polymorphism on the Progression of IgA Nephropathy
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Oh YK, Kwon DY, Zheng SH, Oh KH, Kim HL, Kim KS, Kim YS, Ahn C, Han JS, Kim S, Lee JS
- KMID: 2254480
- Korean J Nephrol.
- 2001 Jan;20(1):59-66.
Uteroglobin(UG) is an anti-inflammatory/immunomodulatory protein secreted by the epithelial cells of vertebrates. Targeted disruption of UG rendered mouse glomerulonephritis resembling IgA nephropathy(IgAN). Sequence analysis on exon 1 of UG showed... -
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- Post-transcriptional control of c-erb B-2 overexpression in stomach cancer cells
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Bae CD, Juhnn YS, Park JB
- KMID: 755111
- Exp Mol Med.
- 2001 Mar;33(1):15-19.
The growth factor receptor oncogene, c-erb B-2, is frequently overexpressed in the adenocarcinomas of breast, ovary, lung and stomach. Although the mechanism of erb B-2 overexpression is thought as the... -
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- Hepatitis G Virus Infection Rate in Blood Donors, Hemodialysis Patients and Hepatitis C Infected Patients
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Kim KY, Kim SC, Lee WK, Kim JS, Suh JS, Song KE, Cho DK, Kim JG, Song DH
- KMID: 2089544
- Korean J Clin Pathol.
- 1998 Sep;18(3):433-441.
BACKGROUND: A recently identified Flaviviridae-like agent, termed hepatitis G virus (HGV), has been recognized as a non A-E hepatitis agent, but its relation to liver disease and transmission mode are... -
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